Hubbi ME - Search Results

1

Lactate-dependent chaperone-mediated autophagy induces oscillatory HIF-1α activity promoting proliferation of hypoxic cells.

Kshitiz, Afzal J, Suhail Y, Chang H, Hubbi ME, Hamidzadeh A, Goyal R, Liu Y, Sun P, Nicoli S, Dang CV, Levchenko A. Kshitiz, et al. Among authors: hubbi me. Cell Syst. 2022 Dec 21;13(12):1048-1064.e7. doi: 10.1016/j.cels.2022.11.003. Epub 2022 Dec 2. Cell Syst. 2022. PMID: 36462504 Free PMC article.

2

A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication.

Hubbi ME, Kshitiz, Gilkes DM, Rey S, Wong CC, Luo W, Kim DH, Dang CV, Levchenko A, Semenza GL. Hubbi ME, et al. Sci Signal. 2013 Feb 12;6(262):ra10. doi: 10.1126/scisignal.2003417. Sci Signal. 2013. PMID: 23405012 Free PMC article.

3

Chaperone-mediated autophagy targets hypoxia-inducible factor-1α (HIF-1α) for lysosomal degradation.

Hubbi ME, Hu H, Kshitiz, Ahmed I, Levchenko A, Semenza GL. Hubbi ME, et al. J Biol Chem. 2013 Apr 12;288(15):10703-14. doi: 10.1074/jbc.M112.414771. Epub 2013 Mar 1. J Biol Chem. 2013. PMID: 23457305 Free PMC article.

4

Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors.

Kshitiz, Hubbi ME, Ahn EH, Downey J, Afzal J, Kim DH, Rey S, Chang C, Kundu A, Semenza GL, Abraham RM, Levchenko A. Kshitiz, et al. Among authors: hubbi me. Sci Signal. 2012 Jun 5;5(227):ra41. doi: 10.1126/scisignal.2003002. Sci Signal. 2012. PMID: 22669846 Free PMC article.

5

Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression.

Hubbi ME, Gilkes DM, Hu H, Kshitiz, Ahmed I, Semenza GL. Hubbi ME, et al. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3325-34. doi: 10.1073/pnas.1412840111. Epub 2014 Jul 28. Proc Natl Acad Sci U S A. 2014. PMID: 25071185 Free PMC article.

6

Sirtuin-7 inhibits the activity of hypoxia-inducible factors.

Hubbi ME, Hu H, Kshitiz, Gilkes DM, Semenza GL. Hubbi ME, et al. J Biol Chem. 2013 Jul 19;288(29):20768-20775. doi: 10.1074/jbc.M113.476903. Epub 2013 Jun 9. J Biol Chem. 2013. PMID: 23750001 Free PMC article.

7

Control of the interface between heterotypic cell populations reveals the mechanism of intercellular transfer of signaling proteins.

Kshitiz, Afzal J, Suhail Y, Ahn EH, Goyal R, Hubbi ME, Hussaini Q, Ellison DD, Goyal J, Nacev B, Kim DH, Lee JH, Frankel S, Gray K, Bankoti R, Chien AJ, Levchenko A. Kshitiz, et al. Among authors: hubbi me. Integr Biol (Camb). 2015 Mar;7(3):364-72. doi: 10.1039/c4ib00209a. Integr Biol (Camb). 2015. PMID: 25784457 Free PMC article.

8

Bcl-xL Enforces a Slow-Cycling State Necessary for Survival in the Nutrient-Deprived Microenvironment of Pancreatic Cancer.

Sela Y, Li J, Maheswaran S, Norgard R, Yuan S, Hubbi M, Doepner M, Xu JP, Ho ES, Mesaros C, Sheehan C, Croley G, Muir A, Blair IA, Shalem O, Dang CV, Stanger BZ. Sela Y, et al. Cancer Res. 2022 May 16;82(10):1890-1908. doi: 10.1158/0008-5472.CAN-22-0431. Cancer Res. 2022. PMID: 35315913 Free PMC article.

9

An essential role for chaperone-mediated autophagy in cell cycle progression.

Hubbi ME, Semenza GL. Hubbi ME, et al. Autophagy. 2015;11(5):850-1. doi: 10.1080/15548627.2015.1037063. Autophagy. 2015. PMID: 25945892 Free PMC article.

10

MCM proteins are negative regulators of hypoxia-inducible factor 1.

Hubbi ME, Luo W, Baek JH, Semenza GL. Hubbi ME, et al. Mol Cell. 2011 Jun 10;42(5):700-12. doi: 10.1016/j.molcel.2011.03.029. Mol Cell. 2011. PMID: 21658608 Free PMC article.

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