Gonsky R - Search Results

1

Diagnostic and therapeutic potential of RNASET2 in Crohn's disease: Disease-risk polymorphism modulates allelic-imbalance in expression and circulating protein levels and recombinant-RNASET2 attenuates pro-inflammatory cytokine secretion.

Biener-Ramanujan E, Rosier F, Coetzee SG, McGovern DDP, Hazelett D, Targan SR, Gonsky R. Biener-Ramanujan E, et al. Among authors: gonsky r. Front Immunol. 2022 Nov 16;13:999155. doi: 10.3389/fimmu.2022.999155. eCollection 2022. Front Immunol. 2022. PMID: 36466822 Free PMC article.

2

Association of Ribonuclease T2 Gene Polymorphisms With Decreased Expression and Clinical Characteristics of Severity in Crohn's Disease.

Gonsky R, Fleshner P, Deem RL, Biener-Ramanujan E, Li D, Potdar AA, Bilsborough J, Yang S, McGovern DPB, Targan SR. Gonsky R, et al. Gastroenterology. 2017 Jul;153(1):219-232. doi: 10.1053/j.gastro.2017.04.002. Epub 2017 Apr 9. Gastroenterology. 2017. PMID: 28400196 Free PMC article.

3

Activation of the CD2 pathway in lamina propria T cells up-regulates functionally active AP-1 binding to the IL-2 promoter, resulting in messenger RNA transcription and IL-2 secretion.

Gonsky R, Deem RL, Hughes CC, Targan SR. Gonsky R, et al. J Immunol. 1998 May 15;160(10):4914-22. J Immunol. 1998. PMID: 9590239

4

CD28 costimulation augments IL-2 secretion of activated lamina propria T cells by increasing mRNA stability without enhancing IL-2 gene transactivation.

Gonsky R, Deem RL, Lee DH, Chen A, Targan SR. Gonsky R, et al. J Immunol. 1999 Jun 1;162(11):6621-9. J Immunol. 1999. PMID: 10352279

5

Mucosa-specific targets for regulation of IFN-gamma expression: lamina propria T cells use different cis-elements than peripheral blood T cells to regulate transactivation of IFN-gamma expression.

Gonsky R, Deem RL, Bream JH, Lee DH, Young HA, Targan SR. Gonsky R, et al. J Immunol. 2000 Feb 1;164(3):1399-407. doi: 10.4049/jimmunol.164.3.1399. J Immunol. 2000. PMID: 10640755

6

CD2 mediates activation of the IFN-gamma intronic STAT binding region in mucosal T cells.

Gonsky R, Deem RL, Young HA, Targan SR. Gonsky R, et al. Eur J Immunol. 2003 May;33(5):1152-62. doi: 10.1002/eji.200322875. Eur J Immunol. 2003. PMID: 12731040 Free article.

7

Enhancer role of STAT5 in CD2 activation of IFN-gamma gene expression.

Gonsky R, Deem RL, Bream J, Young HA, Targan SR. Gonsky R, et al. J Immunol. 2004 Nov 15;173(10):6241-7. doi: 10.4049/jimmunol.173.10.6241. J Immunol. 2004. PMID: 15528362

8

Microbial induction of inflammatory bowel disease associated gene TL1A (TNFSF15) in antigen presenting cells.

Shih DQ, Kwan LY, Chavez V, Cohavy O, Gonsky R, Chang EY, Chang C, Elson CO, Targan SR. Shih DQ, et al. Among authors: gonsky r. Eur J Immunol. 2009 Nov;39(11):3239-50. doi: 10.1002/eji.200839087. Eur J Immunol. 2009. PMID: 19839006 Free PMC article.

9

Functional signaling of membrane-bound TL1A induces IFN-gamma expression.

Biener-Ramanujan E, Gonsky R, Ko B, Targan SR. Biener-Ramanujan E, et al. Among authors: gonsky r. FEBS Lett. 2010 Jun 3;584(11):2376-80. doi: 10.1016/j.febslet.2010.04.030. Epub 2010 Apr 18. FEBS Lett. 2010. PMID: 20403353 Free article.

10

Insights into TL1A and IBD pathogenesis.

Shih DQ, Michelsen KS, Barrett RJ, Biener-Ramanujan E, Gonsky R, Zhang X, Targan SR. Shih DQ, et al. Among authors: gonsky r. Adv Exp Med Biol. 2011;691:279-88. doi: 10.1007/978-1-4419-6612-4_29. Adv Exp Med Biol. 2011. PMID: 21153332 Review. No abstract available.

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