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Funnel metadynamics and behavioral studies reveal complex effect of D2AAK1 ligand on anxiety-like processes.
Bartuzi D, Kędzierska E, Targowska-Duda KM, Koszła O, Wróbel TM, Jademyr S, Karcz T, Szczepańska K, Stępnicki P, Wronikowska-Denysiuk O, Biała G, Handzlik J, Kristensen JL, Poso A, Kaczor AA. Bartuzi D, et al. Among authors: kaczor aa. Sci Rep. 2022 Dec 7;12(1):21192. doi: 10.1038/s41598-022-25478-7. Sci Rep. 2022. PMID: 36476619 Free PMC article.
Chiral 1,3,4-oxadiazol-2-ones as highly selective FAAH inhibitors.
Patel JZ, Parkkari T, Laitinen T, Kaczor AA, Saario SM, Savinainen JR, Navia-Paldanius D, Cipriano M, Leppänen J, Koshevoy IO, Poso A, Fowler CJ, Laitinen JT, Nevalainen T. Patel JZ, et al. Among authors: kaczor aa. J Med Chem. 2013 Nov 14;56(21):8484-96. doi: 10.1021/jm400923s. Epub 2013 Oct 22. J Med Chem. 2013. PMID: 24083878
Synthesis, in vitro and in vivo studies, and molecular modeling of N-alkylated dextromethorphan derivatives as non-competitive inhibitors of α3β4 nicotinic acetylcholine receptor.
Jozwiak K, Targowska-Duda KM, Kaczor AA, Kozak J, Ligeza A, Szacon E, Wrobel TM, Budzynska B, Biala G, Fornal E, Poso A, Wainer IW, Matosiuk D. Jozwiak K, et al. Among authors: kaczor aa. Bioorg Med Chem. 2014 Dec 15;22(24):6846-56. doi: 10.1016/j.bmc.2014.10.036. Epub 2014 Oct 31. Bioorg Med Chem. 2014. PMID: 25464883
Pharmacological and molecular studies on the interaction of varenicline with different nicotinic acetylcholine receptor subtypes. Potential mechanism underlying partial agonism at human α4β2 and α3β4 subtypes.
Arias HR, Feuerbach D, Targowska-Duda K, Kaczor AA, Poso A, Jozwiak K. Arias HR, et al. Among authors: kaczor aa. Biochim Biophys Acta. 2015 Feb;1848(2):731-41. doi: 10.1016/j.bbamem.2014.11.003. Epub 2014 Dec 2. Biochim Biophys Acta. 2015. PMID: 25475645 Free article.
Synthesis, central nervous system activity and structure-activity relationship of N-substituted derivatives of 1-arylimidazolidyn-2-ylideneurea and products of their cyclization.
Szacoń E, Rządkowska M, Kaczor AA, Kędzierska E, Mazur A, Fidecka S, Matosiuk D. Szacoń E, et al. Among authors: kaczor aa. J Enzyme Inhib Med Chem. 2015;30(5):746-60. doi: 10.3109/14756366.2014.965699. Epub 2015 Feb 11. J Enzyme Inhib Med Chem. 2015. PMID: 25669349 Free article.
104 results