Dreveny I - Search Results

1

Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.

Jin Q, Gutierrez Diaz B, Pieters T, Zhou Y, Narang S, Fijalkwoski I, Borin C, Van Laere J, Payton M, Cho BK, Han C, Sun L, Serafin V, Yacu G, Von Loocke W, Basso G, Veltri G, Dreveny I, Ben-Sahra I, Goo YA, Safgren SL, Tsai YC, Bornhauser B, Suraneni PK, Gaspar-Maia A, Kandela I, Van Vlierberghe P, Crispino JD, Tsirigos A, Ntziachristos P. Jin Q, et al. Among authors: dreveny i. Sci Adv. 2022 Dec 9;8(49):eabq8437. doi: 10.1126/sciadv.abq8437. Epub 2022 Dec 9. Sci Adv. 2022. PMID: 36490346 Free PMC article.

2

Structure and catalytic regulatory function of ubiquitin specific protease 11 N-terminal and ubiquitin-like domains.

Harper S, Gratton HE, Cornaciu I, Oberer M, Scott DJ, Emsley J, Dreveny I. Harper S, et al. Among authors: dreveny i. Biochemistry. 2014 May 13;53(18):2966-78. doi: 10.1021/bi500116x. Epub 2014 Apr 29. Biochemistry. 2014. PMID: 24724799 Free PMC article.

3

The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel.

Ward SJ, Gratton HE, Indrayudha P, Michavila C, Mukhopadhyay R, Maurer SK, Caulton SG, Emsley J, Dreveny I. Ward SJ, et al. Among authors: dreveny i. J Biol Chem. 2018 Nov 9;293(45):17362-17374. doi: 10.1074/jbc.RA118.003857. Epub 2018 Sep 18. J Biol Chem. 2018. PMID: 30228188 Free PMC article.

4

Discovery of peptide ligands targeting a specific ubiquitin-like domain-binding site in the deubiquitinase USP11.

Spiliotopoulos A, Blokpoel Ferreras L, Densham RM, Caulton SG, Maddison BC, Morris JR, Dixon JE, Gough KC, Dreveny I. Spiliotopoulos A, et al. Among authors: dreveny i. J Biol Chem. 2019 Jan 11;294(2):424-436. doi: 10.1074/jbc.RA118.004469. Epub 2018 Oct 29. J Biol Chem. 2019. PMID: 30373771 Free PMC article.

5

Structure of the USP15 N-terminal domains: a β-hairpin mediates close association between the DUSP and UBL domains.

Harper S, Besong TM, Emsley J, Scott DJ, Dreveny I. Harper S, et al. Among authors: dreveny i. Biochemistry. 2011 Sep 20;50(37):7995-8004. doi: 10.1021/bi200726e. Epub 2011 Aug 26. Biochemistry. 2011. PMID: 21848306

6

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

Sanchez-Bailon MP, Choi SY, Dufficy ER, Sharma K, McNee GS, Gunnell E, Chiang K, Sahay D, Maslen S, Stewart GS, Skehel JM, Dreveny I, Davies CC. Sanchez-Bailon MP, et al. Among authors: dreveny i. Nat Commun. 2021 Nov 2;12(1):6313. doi: 10.1038/s41467-021-26413-6. Nat Commun. 2021. PMID: 34728620 Free PMC article.

7

Coagulation factor XII protease domain crystal structure.

Pathak M, Wilmann P, Awford J, Li C, Hamad BK, Fischer PM, Dreveny I, Dekker LV, Emsley J. Pathak M, et al. Among authors: dreveny i. J Thromb Haemost. 2015 Apr;13(4):580-91. doi: 10.1111/jth.12849. Epub 2015 Mar 11. J Thromb Haemost. 2015. PMID: 25604127 Free PMC article.

8

Crystal structures of the recombinant β-factor XIIa protease with bound Thr-Arg and Pro-Arg substrate mimetics.

Pathak M, Manna R, Li C, Kaira BG, Hamad BK, Belviso BD, Bonturi CR, Dreveny I, Fischer PM, Dekker LV, Oliva MLV, Emsley J. Pathak M, et al. Among authors: dreveny i. Acta Crystallogr D Struct Biol. 2019 Jun 1;75(Pt 6):578-591. doi: 10.1107/S2059798319006910. Epub 2019 Jun 4. Acta Crystallogr D Struct Biol. 2019. PMID: 31205020

9

Structural and biochemical evaluation of bisubstrate inhibitors of protein arginine N-methyltransferases PRMT1 and CARM1 (PRMT4).

Gunnell EA, Al-Noori A, Muhsen U, Davies CC, Dowden J, Dreveny I. Gunnell EA, et al. Among authors: dreveny i. Biochem J. 2020 Feb 28;477(4):787-800. doi: 10.1042/BCJ20190826. Biochem J. 2020. PMID: 32011657 Free PMC article.

10

The double PHD finger domain of MOZ/MYST3 induces α-helical structure of the histone H3 tail to facilitate acetylation and methylation sampling and modification.

Dreveny I, Deeves SE, Fulton J, Yue B, Messmer M, Bhattacharya A, Collins HM, Heery DM. Dreveny I, et al. Nucleic Acids Res. 2014 Jan;42(2):822-35. doi: 10.1093/nar/gkt931. Epub 2013 Oct 22. Nucleic Acids Res. 2014. PMID: 24150941 Free PMC article.

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