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Page 1
Exposing 24-hour cycles in bile acids of male humans.
Bello AT, Sarafian MH, Wimborne EA, Middleton B, Revell VL, Raynaud FI, Chowdhury NR, van der Veen DR, Skene DJ, Swann JR. Bello AT, et al. Among authors: sarafian mh. Nat Commun. 2024 Nov 19;15(1):10014. doi: 10.1038/s41467-024-53673-9. Nat Commun. 2024. PMID: 39562795 Free PMC article.
Deep longitudinal multi-omics analysis of Bordetella pertussis cultivated in bioreactors highlights medium starvations and transitory metabolisms, associated to vaccine antigen biosynthesis variations and global virulence regulation.
Anziani P, Becker J, Mignon C, Arnaud-Barbe N, Courtois V, Izac M, Pizzato R, Abi-Ghanem J, Tran VD, Sarafian M, Bunescu A, Garnier D, Abachin E, Renauld-Mongénie G, Guyard C. Anziani P, et al. Among authors: sarafian m. Front Microbiol. 2023 Feb 14;14:1036386. doi: 10.3389/fmicb.2023.1036386. eCollection 2023. Front Microbiol. 2023. PMID: 36876086 Free PMC article.
Roux-en-Y gastric bypass-induced bacterial perturbation contributes to altered host-bacterial co-metabolic phenotype.
Li JV, Ashrafian H, Sarafian M, Homola D, Rushton L, Barker G, Cabrera PM, Lewis MR, Darzi A, Lin E, Gletsu-Miller NA, Atkin SL, Sathyapalan T, Gooderham NJ, Nicholson JK, Marchesi JR, Athanasiou T, Holmes E. Li JV, et al. Among authors: sarafian m. Microbiome. 2021 Jun 14;9(1):139. doi: 10.1186/s40168-021-01086-x. Microbiome. 2021. PMID: 34127058 Free PMC article.
Differences in amino acid and lipid metabolism distinguish Crohn's from idiopathic/cryptoglandular perianal fistulas by tissue metabonomic profiling and may offer clues to underlying pathogenesis.
Adegbola SO, Sarafian M, Sahnan K, Ding NS, Faiz OD, Warusavitarne J, Phillips RKS, Tozer PJ, Holmes E, Hart AL. Adegbola SO, et al. Among authors: sarafian m. Eur J Gastroenterol Hepatol. 2021 Dec 1;33(12):1469-1479. doi: 10.1097/MEG.0000000000001976. Eur J Gastroenterol Hepatol. 2021. PMID: 33337668
Enhanced Microbial Bile Acid Deconjugation and Impaired Ileal Uptake in Pregnancy Repress Intestinal Regulation of Bile Acid Synthesis.
Ovadia C, Perdones-Montero A, Spagou K, Smith A, Sarafian MH, Gomez-Romero M, Bellafante E, Clarke LCD, Sadiq F, Nikolova V, Mitchell A, Dixon PH, Santa-Pinter N, Wahlström A, Abu-Hayyeh S, Walters JRF, Marschall HU, Holmes E, Marchesi JR, Williamson C. Ovadia C, et al. Among authors: sarafian mh. Hepatology. 2019 Jul;70(1):276-293. doi: 10.1002/hep.30661. Epub 2019 May 21. Hepatology. 2019. PMID: 30983011 Free PMC article.
Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma-Application to Clinical and Epidemiology Cohorts.
Whiley L, Nye LC, Grant I, Andreas N, Chappell KE, Sarafian MH, Misra R, Plumb RS, Lewis MR, Nicholson JK, Holmes E, Swann JR, Wilson ID. Whiley L, et al. Among authors: sarafian mh. Anal Chem. 2019 Apr 16;91(8):5207-5216. doi: 10.1021/acs.analchem.8b05884. Epub 2019 Mar 25. Anal Chem. 2019. PMID: 30848589 Free PMC article.
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