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KMT2D deficiency drives lung squamous cell carcinoma and hypersensitivity to RTK-RAS inhibition.
Pan Y, Han H, Hu H, Wang H, Song Y, Hao Y, Tong X, Patel AS, Misirlioglu S, Tang S, Huang HY, Geng K, Chen T, Karatza A, Sherman F, Labbe KE, Yang F, Chafitz A, Peng C, Guo C, Moreira AL, Velcheti V, Lau SCM, Sui P, Chen H, Diehl JA, Rustgi AK, Bass AJ, Poirier JT, Zhang X, Ji H, Zhang H, Wong KK. Pan Y, et al. Among authors: patel as. Cancer Cell. 2023 Jan 9;41(1):88-105.e8. doi: 10.1016/j.ccell.2022.11.015. Epub 2022 Dec 15. Cancer Cell. 2023. PMID: 36525973 Free PMC article.
Adeno-to-squamous transition drives resistance to KRAS inhibition in LKB1 mutant lung cancer.
Tong X, Patel AS, Kim E, Li H, Chen Y, Li S, Liu S, Dilly J, Kapner KS, Zhang N, Xue Y, Hover L, Mukhopadhyay S, Sherman F, Myndzar K, Sahu P, Gao Y, Li F, Li F, Fang Z, Jin Y, Gao J, Shi M, Sinha S, Chen L, Chen Y, Kheoh T, Yang W, Yanai I, Moreira AL, Velcheti V, Neel BG, Hu L, Christensen JG, Olson P, Gao D, Zhang MQ, Aguirre AJ, Wong KK, Ji H. Tong X, et al. Among authors: patel as. Cancer Cell. 2024 Mar 11;42(3):413-428.e7. doi: 10.1016/j.ccell.2024.01.012. Epub 2024 Feb 22. Cancer Cell. 2024. PMID: 38402609 Free article.
Cellular adaptation to cancer therapy along a resistance continuum.
França GS, Baron M, King BR, Bossowski JP, Bjornberg A, Pour M, Rao A, Patel AS, Misirlioglu S, Barkley D, Tang KH, Dolgalev I, Liberman DA, Avital G, Kuperwaser F, Chiodin M, Levine DA, Papagiannakopoulos T, Marusyk A, Lionnet T, Yanai I. França GS, et al. Among authors: patel as. Nature. 2024 Jul;631(8022):876-883. doi: 10.1038/s41586-024-07690-9. Epub 2024 Jul 10. Nature. 2024. PMID: 38987605
Transcriptional Circuitry of NKX2-1 and SOX1 Defines an Unrecognized Lineage Subtype of Small-Cell Lung Cancer.
Kong R, Patel AS, Sato T, Jiang F, Yoo S, Bao L, Sinha A, Tian Y, Fridrikh M, Liu S, Feng J, He X, Jiang J, Ma Y, Grullon K, Yang D, Powell CA, Beasley MB, Zhu J, Snyder EL, Li S, Watanabe H. Kong R, et al. Among authors: patel as. Am J Respir Crit Care Med. 2022 Dec 15;206(12):1480-1494. doi: 10.1164/rccm.202110-2358OC. Am J Respir Crit Care Med. 2022. PMID: 35848993 Free PMC article.
Integrative network analysis of early-stage lung adenocarcinoma identifies aurora kinase inhibition as interceptor of invasion and progression.
Yoo S, Sinha A, Yang D, Altorki NK, Tandon R, Wang W, Chavez D, Lee E, Patel AS, Sato T, Kong R, Ding B, Schadt EE, Watanabe H, Massion PP, Borczuk AC, Zhu J, Powell CA. Yoo S, et al. Among authors: patel as. Nat Commun. 2022 Mar 24;13(1):1592. doi: 10.1038/s41467-022-29230-7. Nat Commun. 2022. PMID: 35332150 Free PMC article.
Leptin signaling maintains autonomic stability during severe influenza infection in mice.
Muñoz-Rojas AR, Wang AC, Pomeranz LE, Reizis EL, Stout-Delgado HW, Miranda IC, Rajagopalan K, Gwatiringa T, Fan RR, Huda AA, Maskey N, Olumuyide RP, Patel AS, Friedman JM, Mathis D, Rajagopalan KN. Muñoz-Rojas AR, et al. Among authors: patel as. J Clin Invest. 2024 Oct 31;135(1):e182550. doi: 10.1172/JCI182550. J Clin Invest. 2024. PMID: 39480494 Free PMC article. No abstract available.
416 results