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The upregulation of NLRP3 inflammasome in dorsal root ganglion by ten-eleven translocation methylcytosine dioxygenase 2 (TET2) contributed to diabetic neuropathic pain in mice.
Chen W, Wang X, Sun Q, Zhang Y, Liu J, Hu T, Wu W, Wei C, Liu M, Ding Y, Liu D, Chong Y, Wang P, Zhu H, Cui W, Zhang J, Li Q, Yang F. Chen W, et al. Among authors: wang x, wang p. J Neuroinflammation. 2022 Dec 16;19(1):302. doi: 10.1186/s12974-022-02669-7. J Neuroinflammation. 2022. PMID: 36527131 Free PMC article.
IRG1/itaconate increases IL-10 release to alleviate mechanical and thermal hypersensitivity in mice after nerve injury.
Sun Q, Hu T, Zhang Y, Wang X, Liu J, Chen W, Wei C, Liu D, Wu W, Lan T, Ding Y, Luo Z, Liu M, Shen D, Xiao Z, Hu L, Pang M, Ma Y, Shi L, Wang P, Zhang J, Li Q, Yang F. Sun Q, et al. Among authors: wang x, wang p. Front Immunol. 2022 Oct 13;13:1012442. doi: 10.3389/fimmu.2022.1012442. eCollection 2022. Front Immunol. 2022. PMID: 36311727 Free PMC article.
Inhibition of the LRRC8A channel promotes microglia/macrophage phagocytosis and improves outcomes after intracerebral hemorrhagic stroke.
Liu J, Shen D, Wei C, Wu W, Luo Z, Hu L, Xiao Z, Hu T, Sun Q, Wang X, Ding Y, Liu M, Pang M, Gai K, Ma Y, Tian Y, Yu Y, Wang P, Guan Y, Xu M, Yang F, Li Q. Liu J, et al. Among authors: wang x, wang p. iScience. 2022 Nov 13;25(12):105527. doi: 10.1016/j.isci.2022.105527. eCollection 2022 Dec 22. iScience. 2022. PMID: 36465125 Free PMC article.
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