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Synaptic resilience is associated with maintained cognition during ageing.
King D, Holt K, Toombs J, He X, Dando O, Okely JA, Tzioras M, Rose J, Gunn C, Correia A, Montero C, McAlister H, Tulloch J, Lamont D, Taylor AM, Harris SE, Redmond P, Cox SR, Henstridge CM, Deary IJ, Smith C, Spires-Jones TL. King D, et al. Among authors: he x. Alzheimers Dement. 2023 Jun;19(6):2560-2574. doi: 10.1002/alz.12894. Epub 2022 Dec 22. Alzheimers Dement. 2023. PMID: 36547260 Free PMC article.
Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology.
Jiwaji Z, Tiwari SS, Avilés-Reyes RX, Hooley M, Hampton D, Torvell M, Johnson DA, McQueen J, Baxter P, Sabari-Sankar K, Qiu J, He X, Fowler J, Febery J, Gregory J, Rose J, Tulloch J, Loan J, Story D, McDade K, Smith AM, Greer P, Ball M, Kind PC, Matthews PM, Smith C, Dando O, Spires-Jones TL, Johnson JA, Chandran S, Hardingham GE. Jiwaji Z, et al. Among authors: he x. Nat Commun. 2022 Jan 10;13(1):135. doi: 10.1038/s41467-021-27702-w. Nat Commun. 2022. PMID: 35013236 Free PMC article.
Synaptic gene expression changes in frontotemporal dementia due to the MAPT 10+16 mutation.
Dando O, McGeachan R, McQueen J, Baxter P, Rockley N, McAlister H, Prasad A, He X, King D, Rose J, Jones PB, Tulloch J, Chandran S, Smith C, Hardingham G, Spires-Jones TL. Dando O, et al. Among authors: he x. medRxiv [Preprint]. 2024 Apr 12:2024.04.09.24305501. doi: 10.1101/2024.04.09.24305501. medRxiv. 2024. Update in: Neuropathol Appl Neurobiol. 2024 Aug;50(4):e13006. doi: 10.1111/nan.13006 PMID: 38645146 Free PMC article. Updated. Preprint.
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