Moffett RC - Search Results

1

Evidence for Involvement of GIP and GLP-1 Receptors and the Gut-Gonadal Axis in Regulating Female Reproductive Function in Mice.

Khan D, Ojo OO, Woodward OR, Lewis JE, Sridhar A, Gribble FM, Reimann F, Flatt PR, Moffett RC. Khan D, et al. Among authors: moffett rc. Biomolecules. 2022 Nov 23;12(12):1736. doi: 10.3390/biom12121736. Biomolecules. 2022. PMID: 36551163 Free PMC article.

2

Beneficial effects of the novel cholecystokinin agonist (pGlu-Gln)-CCK-8 in mouse models of obesity/diabetes.

Irwin N, Frizelle P, Montgomery IA, Moffett RC, O'Harte FPM, Flatt PR. Irwin N, et al. Among authors: moffett rc. Diabetologia. 2012 Oct;55(10):2747-2758. doi: 10.1007/s00125-012-2654-6. Epub 2012 Jul 20. Diabetologia. 2012. PMID: 22814764

3

Chemical cholecystokinin receptor activation protects against obesity-diabetes in high fat fed mice and has sustainable beneficial effects in genetic ob/ob mice.

Irwin N, Montgomery IA, Moffett RC, Flatt PR. Irwin N, et al. Among authors: moffett rc. Biochem Pharmacol. 2013 Jan 1;85(1):81-91. doi: 10.1016/j.bcp.2012.10.008. Epub 2012 Oct 17. Biochem Pharmacol. 2013. PMID: 23085436

4

Beneficial effects of parenteral GLP-1 delivery by cell therapy in insulin-deficient streptozotocin diabetic mice.

Vasu S, Moffett RC, McCluskey JT, Hamid MH, Irwin N, Flatt PR. Vasu S, et al. Among authors: moffett rc. Gene Ther. 2013 Nov;20(11):1077-84. doi: 10.1038/gt.2013.33. Epub 2013 Jun 20. Gene Ther. 2013. PMID: 23784442

5

Alterations of glucose-dependent insulinotropic polypeptide and expression of genes involved in mammary gland and adipose tissue lipid metabolism during pregnancy and lactation.

Moffett RC, Irwin N, Francis JM, Flatt PR. Moffett RC, et al. PLoS One. 2013 Nov 13;8(11):e78560. doi: 10.1371/journal.pone.0078560. eCollection 2013. PLoS One. 2013. PMID: 24236022 Free PMC article.

6

Incretin receptor null mice reveal key role of GLP-1 but not GIP in pancreatic beta cell adaptation to pregnancy.

Moffett RC, Vasu S, Thorens B, Drucker DJ, Flatt PR. Moffett RC, et al. PLoS One. 2014 Jun 13;9(6):e96863. doi: 10.1371/journal.pone.0096863. eCollection 2014. PLoS One. 2014. PMID: 24927416 Free PMC article.

7

Role of endogenous GLP-1 and GIP in beta cell compensatory responses to insulin resistance and cellular stress.

Vasu S, Moffett RC, Thorens B, Flatt PR. Vasu S, et al. Among authors: moffett rc. PLoS One. 2014 Jun 26;9(6):e101005. doi: 10.1371/journal.pone.0101005. eCollection 2014. PLoS One. 2014. PMID: 24967820 Free PMC article.

8

Positive effects of GLP-1 receptor activation with liraglutide on pancreatic islet morphology and metabolic control in C57BL/KsJ db/db mice with degenerative diabetes.

Moffett RC, Patterson S, Irwin N, Flatt PR. Moffett RC, et al. Diabetes Metab Res Rev. 2015 Mar;31(3):248-55. doi: 10.1002/dmrr.2608. Epub 2014 Nov 18. Diabetes Metab Res Rev. 2015. PMID: 25256010

9

Responses of GLP1-secreting L-cells to cytotoxicity resemble pancreatic β-cells but not α-cells.

Vasu S, Moffett RC, McClenaghan NH, Flatt PR. Vasu S, et al. Among authors: moffett rc. J Mol Endocrinol. 2015 Feb;54(1):91-104. doi: 10.1530/JME-14-0214. Epub 2014 Dec 19. J Mol Endocrinol. 2015. PMID: 25527608

10

Functional GIP receptors play a major role in islet compensatory response to high fat feeding in mice.

Moffett RC, Vasu S, Flatt PR. Moffett RC, et al. Biochim Biophys Acta. 2015 Jun;1850(6):1206-14. doi: 10.1016/j.bbagen.2015.02.006. Epub 2015 Feb 14. Biochim Biophys Acta. 2015. PMID: 25688757

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