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Lipoic/Capsaicin-Related Amides: Synthesis and Biological Characterization of New TRPV1 Agonists Endowed with Protective Properties against Oxidative Stress.
Brizzi A, Maramai S, Aiello F, Baratto MC, Corelli F, Mugnaini C, Paolino M, Scorzelli F, Aldinucci C, De Petrocellis L, Signorini C, Pessina F. Brizzi A, et al. Among authors: paolino m. Int J Mol Sci. 2022 Nov 5;23(21):13580. doi: 10.3390/ijms232113580. Int J Mol Sci. 2022. PMID: 36362364 Free PMC article.
In Silico-Guided Rational Drug Design and Synthesis of Novel 4-(Thiophen-2-yl)butanamides as Potent and Selective TRPV1 Agonists.
Romeo I, Brizzi A, Pessina F, Ambrosio FA, Aiello F, Belardo C, Carullo G, Costa G, De Petrocellis L, Frosini M, Luongo L, Maramai S, Paolino M, Moriello AS, Mugnaini C, Scorzelli F, Maione S, Corelli F, Di Marzo V, Alcaro S, Artese A. Romeo I, et al. Among authors: paolino m. J Med Chem. 2023 May 25;66(10):6994-7015. doi: 10.1021/acs.jmedchem.3c00447. Epub 2023 May 16. J Med Chem. 2023. PMID: 37192374
Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor.
Mugnaini C, Kostrzewa M, Casini M, Kumar P, Catallo V, Allarà M, Guastaferro L, Brizzi A, Paolino M, Tafi A, Kapatais C, Giorgi G, Vacondio F, Mor M, Corelli F, Ligresti A. Mugnaini C, et al. Among authors: paolino m. Molecules. 2023 Jun 24;28(13):4958. doi: 10.3390/molecules28134958. Molecules. 2023. PMID: 37446625 Free PMC article.
163 results