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Antiviral Activity and Crystal Structures of HIV-1 gp120 Antagonists.
Curreli F, Kwon YD, Nicolau I, Burgos G, Altieri A, Kurkin AV, Verardi R, Kwong PD, Debnath AK. Curreli F, et al. Among authors: altieri a. Int J Mol Sci. 2022 Dec 15;23(24):15999. doi: 10.3390/ijms232415999. Int J Mol Sci. 2022. PMID: 36555641 Free PMC article.
Structure-based lead optimization to improve antiviral potency and ADMET properties of phenyl-1H-pyrrole-carboxamide entry inhibitors targeted to HIV-1 gp120.
Curreli F, Belov DS, Kwon YD, Ramesh R, Furimsky AM, O'Loughlin K, Byrge PC, Iyer LV, Mirsalis JC, Kurkin AV, Altieri A, Debnath AK. Curreli F, et al. Among authors: altieri a. Eur J Med Chem. 2018 Jun 25;154:367-391. doi: 10.1016/j.ejmech.2018.04.062. Epub 2018 May 12. Eur J Med Chem. 2018. PMID: 29860061 Free PMC article.
Preclinical Optimization of gp120 Entry Antagonists as anti-HIV-1 Agents with Improved Cytotoxicity and ADME Properties through Rational Design, Synthesis, and Antiviral Evaluation.
Curreli F, Ahmed S, Benedict Victor SM, Iusupov IR, Belov DS, Markov PO, Kurkin AV, Altieri A, Debnath AK. Curreli F, et al. Among authors: altieri a. J Med Chem. 2020 Feb 27;63(4):1724-1749. doi: 10.1021/acs.jmedchem.9b02149. Epub 2020 Feb 17. J Med Chem. 2020. PMID: 32031803 Free PMC article.
284 results