Gochin M - Search Results

1

Targeting a Conserved Lysine in the Hydrophobic Pocket of HIV-1 gp41 Improves Small Molecule Antiviral Activity.

He L, Zhou G, Sofiyev V, Garcia E, Nguyen N, Li KH, Gochin M. He L, et al. Among authors: gochin m. Viruses. 2022 Dec 2;14(12):2703. doi: 10.3390/v14122703. Viruses. 2022. PMID: 36560708 Free PMC article.

2

A fluorescence assay for rapid detection of ligand binding affinity to HIV-1 gp41.

Gochin M, Savage R, Hinckley S, Cai L. Gochin M, et al. Biol Chem. 2006 Apr;387(4):477-83. doi: 10.1515/BC.2006.063. Biol Chem. 2006. PMID: 16606347 Free PMC article.

3

A novel fluorescence intensity screening assay identifies new low-molecular-weight inhibitors of the gp41 coiled-coil domain of human immunodeficiency virus type 1.

Cai L, Gochin M. Cai L, et al. Among authors: gochin m. Antimicrob Agents Chemother. 2007 Jul;51(7):2388-95. doi: 10.1128/AAC.00150-07. Epub 2007 Apr 23. Antimicrob Agents Chemother. 2007. PMID: 17452484 Free PMC article.

4

Artificial ion channel biosensor in human immunodeficiency virus gp41 drug sensing.

Hou Y, Gochin M. Hou Y, et al. Among authors: gochin m. Anal Chem. 2008 Aug 1;80(15):5924-9. doi: 10.1021/ac800511n. Epub 2008 Jul 1. Anal Chem. 2008. PMID: 18590277 Free article.

5

NMR second site screening for structure determination of ligands bound in the hydrophobic pocket of HIV-1 gp41.

Balogh E, Wu D, Zhou G, Gochin M. Balogh E, et al. Among authors: gochin m. J Am Chem Soc. 2009 Mar 4;131(8):2821-3. doi: 10.1021/ja8094558. J Am Chem Soc. 2009. PMID: 19206471 Free PMC article.

6

Stable extended human immunodeficiency virus type 1 gp41 coiled coil as an effective target in an assay for high-affinity fusion inhibitors.

Cai L, Balogh E, Gochin M. Cai L, et al. Among authors: gochin m. Antimicrob Agents Chemother. 2009 Jun;53(6):2444-9. doi: 10.1128/AAC.00150-09. Epub 2009 Apr 13. Antimicrob Agents Chemother. 2009. PMID: 19364877 Free PMC article.

7

The role of amphiphilicity and negative charge in glycoprotein 41 interactions in the hydrophobic pocket.

Gochin M, Cai L. Gochin M, et al. J Med Chem. 2009 Jul 23;52(14):4338-44. doi: 10.1021/jm900190q. J Med Chem. 2009. PMID: 19534533 Free PMC article.

8

Design, synthesis, and evaluation of indole compounds as novel inhibitors targeting Gp41.

Zhou G, Wu D, Hermel E, Balogh E, Gochin M. Zhou G, et al. Among authors: gochin m. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1500-3. doi: 10.1016/j.bmcl.2010.01.111. Epub 2010 Jan 25. Bioorg Med Chem Lett. 2010. PMID: 20153190 Free PMC article.

9

Paramagnetic relaxation assisted docking of a small indole compound in the HIV-1 gp41 hydrophobic pocket.

Gochin M, Zhou G, Phillips AH. Gochin M, et al. ACS Chem Biol. 2011 Mar 18;6(3):267-74. doi: 10.1021/cb100368d. Epub 2011 Jan 7. ACS Chem Biol. 2011. PMID: 21155611 Free PMC article.

10

Development of indole compounds as small molecule fusion inhibitors targeting HIV-1 glycoprotein-41.

Zhou G, Wu D, Snyder B, Ptak RG, Kaur H, Gochin M. Zhou G, et al. Among authors: gochin m. J Med Chem. 2011 Oct 27;54(20):7220-31. doi: 10.1021/jm200791z. Epub 2011 Oct 3. J Med Chem. 2011. PMID: 21928824 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

45 results

Search Page

Filters