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Improved tag-switch method reveals that thioredoxin acts as depersulfidase and controls the intracellular levels of protein persulfidation.
Wedmann R, Onderka C, Wei S, Szijártó IA, Miljkovic JL, Mitrovic A, Lange M, Savitsky S, Yadav PK, Torregrossa R, Harrer EG, Harrer T, Ishii I, Gollasch M, Wood ME, Galardon E, Xian M, Whiteman M, Banerjee R, Filipovic MR. Wedmann R, et al. Among authors: torregrossa r. Chem Sci. 2016 May 25;7(5):3414-3426. doi: 10.1039/c5sc04818d. Epub 2016 Feb 19. Chem Sci. 2016. PMID: 27170841 Free PMC article.
The Mitochondria-Targeted H2S-Donor AP39 in a Murine Model of Combined Hemorrhagic Shock and Blunt Chest Trauma.
Wepler M, Merz T, Wachter U, Vogt J, Calzia E, Scheuerle A, Möller P, Gröger M, Kress S, Fink M, Lukaschewski B, Rumm G, Stahl B, Georgieff M, Huber-Lang M, Torregrossa R, Whiteman M, McCook O, Radermacher P, Hartmann C. Wepler M, et al. Among authors: torregrossa r. Shock. 2019 Aug;52(2):230-239. doi: 10.1097/SHK.0000000000001210. Shock. 2019. PMID: 29927788
Cytochrome c Reduction by H2S Potentiates Sulfide Signaling.
Vitvitsky V, Miljkovic JL, Bostelaar T, Adhikari B, Yadav PK, Steiger AK, Torregrossa R, Pluth MD, Whiteman M, Banerjee R, Filipovic MR. Vitvitsky V, et al. Among authors: torregrossa r. ACS Chem Biol. 2018 Aug 17;13(8):2300-2307. doi: 10.1021/acschembio.8b00463. Epub 2018 Jul 18. ACS Chem Biol. 2018. PMID: 29966080 Free PMC article.
Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration.
Zivanovic J, Kouroussis E, Kohl JB, Adhikari B, Bursac B, Schott-Roux S, Petrovic D, Miljkovic JL, Thomas-Lopez D, Jung Y, Miler M, Mitchell S, Milosevic V, Gomes JE, Benhar M, Gonzalez-Zorn B, Ivanovic-Burmazovic I, Torregrossa R, Mitchell JR, Whiteman M, Schwarz G, Snyder SH, Paul BD, Carroll KS, Filipovic MR. Zivanovic J, et al. Among authors: torregrossa r. Cell Metab. 2019 Dec 3;30(6):1152-1170.e13. doi: 10.1016/j.cmet.2019.10.007. Epub 2019 Nov 14. Cell Metab. 2019. PMID: 31735592 Free PMC article.
51 results