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Optimized LC-MS/MS quantification of tuberculosis drug candidate macozinone (PBTZ169), its dearomatized Meisenheimer Complex and other metabolites, in human plasma and urine.
Desfontaine V, Guinchard S, Marques S, Vocat A, Moulfi F, Versace F, Huser-Pitteloud J, Ivanyuk A, Bardinet C, Makarov V, Ryabova O, André P, Prod'Hom S, Chtioui H, Buclin T, Cole ST, Decosterd L. Desfontaine V, et al. Among authors: moulfi f. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Jan 15;1215:123555. doi: 10.1016/j.jchromb.2022.123555. Epub 2022 Dec 9. J Chromatogr B Analyt Technol Biomed Life Sci. 2023. PMID: 36563654 Free PMC article.