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An epithelial-immune circuit amplifies inflammasome and IL-6 responses to SARS-CoV-2.
Barnett KC, Xie Y, Asakura T, Song D, Liang K, Taft-Benz SA, Guo H, Yang S, Okuda K, Gilmore RC, Loome JF, Oguin Iii TH, Sempowski GD, Randell SH, Heise MT, Lei YL, Boucher RC, Ting JP. Barnett KC, et al. Among authors: sempowski gd. Cell Host Microbe. 2023 Feb 8;31(2):243-259.e6. doi: 10.1016/j.chom.2022.12.005. Epub 2022 Dec 9. Cell Host Microbe. 2023. PMID: 36563691 Free PMC article.
MyD88 provides a protective role in long-term radiation-induced lung injury.
Brickey WJ, Neuringer IP, Walton W, Hua X, Wang EY, Jha S, Sempowski GD, Yang X, Kirby SL, Tilley SL, Ting JP. Brickey WJ, et al. Among authors: sempowski gd. Int J Radiat Biol. 2012 Apr;88(4):335-47. doi: 10.3109/09553002.2012.652723. Epub 2012 Feb 6. Int J Radiat Biol. 2012. PMID: 22248128 Free PMC article.
Radiation combined with thermal injury induces immature myeloid cells.
Mendoza AE, Neely CJ, Charles AG, Kartchner LB, Brickey WJ, Khoury AL, Sempowski GD, Ting JP, Cairns BA, Maile R. Mendoza AE, et al. Among authors: sempowski gd. Shock. 2012 Nov;38(5):532-42. doi: 10.1097/SHK.0b013e31826c5b19. Shock. 2012. PMID: 23042190 Free PMC article.
Source and Purity of Dengue-Viral Preparations Impact Requirement for Enhancing Antibody to Induce Elevated IL-1β Secretion: A Primary Human Monocyte Model.
Callaway JB, Smith SA, Widman DG, McKinnon KP, Scholle F, Sempowski GD, Dittmer DP, Crowe JE Jr, de Silva AM, Ting JP. Callaway JB, et al. Among authors: sempowski gd. PLoS One. 2015 Aug 24;10(8):e0136708. doi: 10.1371/journal.pone.0136708. eCollection 2015. PLoS One. 2015. PMID: 26301593 Free PMC article.
NLRX1 Sequesters STING to Negatively Regulate the Interferon Response, Thereby Facilitating the Replication of HIV-1 and DNA Viruses.
Guo H, König R, Deng M, Riess M, Mo J, Zhang L, Petrucelli A, Yoh SM, Barefoot B, Samo M, Sempowski GD, Zhang A, Colberg-Poley AM, Feng H, Lemon SM, Liu Y, Zhang Y, Wen H, Zhang Z, Damania B, Tsao LC, Wang Q, Su L, Duncan JA, Chanda SK, Ting JP. Guo H, et al. Among authors: sempowski gd. Cell Host Microbe. 2016 Apr 13;19(4):515-528. doi: 10.1016/j.chom.2016.03.001. Cell Host Microbe. 2016. PMID: 27078069 Free PMC article.
A robust microparticle platform for a STING-targeted adjuvant that enhances both humoral and cellular immunity during vaccination.
Junkins RD, Gallovic MD, Johnson BM, Collier MA, Watkins-Schulz R, Cheng N, David CN, McGee CE, Sempowski GD, Shterev I, McKinnon K, Bachelder EM, Ainslie KM, Ting JP. Junkins RD, et al. Among authors: sempowski gd. J Control Release. 2018 Jan 28;270:1-13. doi: 10.1016/j.jconrel.2017.11.030. Epub 2017 Nov 21. J Control Release. 2018. PMID: 29170142 Free PMC article.
203 results