Microglial Trem2 induces synaptic impairment at early stage and prevents amyloidosis at late stage in APP/PS1 mice.
Sheng L, Chen M, Cai K, Song Y, Yu D, Zhang H, Xu G.
Sheng L, et al. Among authors: chen m.
FASEB J. 2019 Sep;33(9):10425-10442. doi: 10.1096/fj.201900527R. Epub 2019 Jun 20.
FASEB J. 2019.
PMID: 31219699
In this study, we highlighted that TREM2 triggers synaptic loss during AD pathology development.-Sheng, L., Chen, M., Cai, K., Song, Y., Yu, D., Zhang, H., Xu, G. Microglial Trem2 induces synaptic impairment at early stage and prevents amyloidosis at late stage in A …
In this study, we highlighted that TREM2 triggers synaptic loss during AD pathology development.-Sheng, L., Chen, M., Cai, K., …