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A comprehensive human embryo reference tool using single-cell RNA-sequencing data.
Zhao C, Plaza Reyes A, Schell JP, Weltner J, Ortega NM, Zheng Y, Björklund ÅK, Baqué-Vidal L, Sokka J, Torokovic R, Cox B, Rossant J, Fu J, Petropoulos S, Lanner F. Zhao C, et al. Among authors: sokka j. Nat Methods. 2024 Nov 14. doi: 10.1038/s41592-024-02493-2. Online ahead of print. Nat Methods. 2024. PMID: 39543283
Chromatin modifier developmental pluripotency associated factor 4 (DPPA4) is a candidate gene for alcohol-induced developmental disorders.
Auvinen P, Vehviläinen J, Marjonen H, Modhukur V, Sokka J, Wallén E, Rämö K, Ahola L, Salumets A, Otonkoski T, Skottman H, Ollikainen M, Trokovic R, Kahila H, Kaminen-Ahola N. Auvinen P, et al. Among authors: sokka j. BMC Med. 2022 Dec 30;20(1):495. doi: 10.1186/s12916-022-02699-1. BMC Med. 2022. PMID: 36581877 Free PMC article.
Transient DUX4 expression in human embryonic stem cells induces blastomere-like expression program that is marked by SLC34A2.
Yoshihara M, Kirjanov I, Nykänen S, Sokka J, Weltner J, Lundin K, Gawriyski L, Jouhilahti EM, Varjosalo M, Tervaniemi MH, Otonkoski T, Trokovic R, Katayama S, Vuoristo S, Kere J. Yoshihara M, et al. Among authors: sokka j. Stem Cell Reports. 2022 Jul 12;17(7):1743-1756. doi: 10.1016/j.stemcr.2022.06.002. Epub 2022 Jun 30. Stem Cell Reports. 2022. PMID: 35777358 Free PMC article.
CRISPR activation enables high-fidelity reprogramming into human pluripotent stem cells.
Sokka J, Yoshihara M, Kvist J, Laiho L, Warren A, Stadelmann C, Jouhilahti EM, Kilpinen H, Balboa D, Katayama S, Kyttälä A, Kere J, Otonkoski T, Weltner J, Trokovic R. Sokka J, et al. Stem Cell Reports. 2022 Feb 8;17(2):413-426. doi: 10.1016/j.stemcr.2021.12.017. Epub 2022 Jan 20. Stem Cell Reports. 2022. PMID: 35063129 Free PMC article.