Lin R - Search Results

1

CJ₂: A Novel Potent Platinum(IV) Prodrug Enhances Chemo-Immunotherapy by Facilitating PD-L1 Degradation in the Cytoplasm and Cytomembrane.

Fan R, Deng A, Qi B, Zhang S, Sang R, Luo L, Gou J, Liu Y, Lin R, Zhao M, Liu Y, Yang L, Cheng M, Wei G. Fan R, et al. Among authors: lin r. J Med Chem. 2023 Jan 12;66(1):875-889. doi: 10.1021/acs.jmedchem.2c01719. Epub 2023 Jan 3. J Med Chem. 2023. PMID: 36594812

2

Degradation of Hexokinase 2 Blocks Glycolysis and Induces GSDME-Dependent Pyroptosis to Amplify Immunogenic Cell Death for Breast Cancer Therapy.

Sang R, Fan R, Deng A, Gou J, Lin R, Zhao T, Hai Y, Song J, Liu Y, Qi B, Du G, Cheng M, Wei G. Sang R, et al. Among authors: lin r. J Med Chem. 2023 Jul 13;66(13):8464-8483. doi: 10.1021/acs.jmedchem.3c00118. Epub 2023 Jun 27. J Med Chem. 2023. PMID: 37376788

3

A novel mitochondria-targeting DHODH inhibitor induces robust ferroptosis and alleviates immune suppression.

Hai Y, Fan R, Zhao T, Lin R, Zhuang J, Deng A, Meng S, Hou Z, Wei G. Hai Y, et al. Among authors: lin r. Pharmacol Res. 2024 Apr;202:107115. doi: 10.1016/j.phrs.2024.107115. Epub 2024 Feb 27. Pharmacol Res. 2024. PMID: 38423231 Free article.

4

Novel Pt(IV) complex OAP2 induces STING activation and pyroptosis via mitochondrial membrane remodeling for synergistic chemo-immunotherapy.

Fan R, Lin R, Zhang S, Deng A, Hai Y, Zhuang J, Liu Y, Cheng M, Wei G. Fan R, et al. Among authors: lin r. Acta Pharm Sin B. 2024 Apr;14(4):1742-1758. doi: 10.1016/j.apsb.2023.11.032. Epub 2023 Dec 16. Acta Pharm Sin B. 2024. PMID: 38572099 Free PMC article.

5

A platinum(IV)-artesunate complex triggers ferroptosis by boosting cytoplasmic and mitochondrial lipid peroxidation to enhance tumor immunotherapy.

Fan R, Deng A, Lin R, Zhang S, Cheng C, Zhuang J, Hai Y, Zhao M, Yang L, Wei G. Fan R, et al. Among authors: lin r. MedComm (2020). 2024 May 20;5(6):e570. doi: 10.1002/mco2.570. eCollection 2024 Jun. MedComm (2020). 2024. PMID: 38774917 Free PMC article.

6

Deep learning-based drug screening for the discovery of potential therapeutic agents for Alzheimer's disease.

Wu T, Lin R, Cui P, Yong J, Yu H, Li Z. Wu T, et al. Among authors: lin r. J Pharm Anal. 2024 Oct;14(10):101022. doi: 10.1016/j.jpha.2024.101022. Epub 2024 Jun 13. J Pharm Anal. 2024. PMID: 39850238 Free PMC article.

7

Versatile poly (deep eutectic solvents) electroactive chitosan eutectogel for infected wound healing and monitoring administration.

Liu S, Zhan J, Liu Z, Tan X, Huang J, Pu C, Lin R, Chen Y, Luo Q, Qiu X, Hou H. Liu S, et al. Among authors: lin r. Carbohydr Polym. 2025 Mar 15;352:123192. doi: 10.1016/j.carbpol.2024.123192. Epub 2024 Dec 25. Carbohydr Polym. 2025. PMID: 39843045

8

Super-enhancers in tumors: unraveling recent advances in their role in Oncogenesis and the emergence of targeted therapies.

Ji Y, Li B, Lin R, Yuan J, Han Y, Du Y, Zhao Y. Ji Y, et al. Among authors: lin r. J Transl Med. 2025 Jan 21;23(1):98. doi: 10.1186/s12967-025-06098-x. J Transl Med. 2025. PMID: 39838405 Free PMC article. Review.

9

A mobile-based multidomain lifestyle intervention using Cognitive Evergreenland for older adults with subjective cognitive decline: a feasibility study.

Lin R, Yan Y, Chen Z, Huang C, Zhao J, Chen M, Li H. Lin R, et al. BMC Geriatr. 2025 Jan 20;25(1):41. doi: 10.1186/s12877-025-05684-4. BMC Geriatr. 2025. PMID: 39833671 Free PMC article.

10

Targeting estrogen-regulated system x_c^- promotes ferroptosis and endocrine sensitivity of ER+ breast cancer.

Cao J, Zhou T, Wu T, Lin R, Huang J, Shi D, Yu J, Ren Y, Qian C, He L, Wu G, Dong Z, Yuan S, Gu H. Cao J, et al. Among authors: lin r. Cell Death Dis. 2025 Jan 20;16(1):30. doi: 10.1038/s41419-025-07354-0. Cell Death Dis. 2025. PMID: 39833180 Free article.

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