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The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis.
Han L, Wu Y, Fang K, Sweeney S, Roesner UK, Parrish M, Patel K, Walter T, Piermattei J, Trimboli A, Lefler J, Timmers CD, Yu XZ, Jin VX, Zimmermann MT, Mathison AJ, Urrutia R, Ostrowski MC, Leone G. Han L, et al. Among authors: mathison aj. Nat Commun. 2023 Jan 3;14(1):1. doi: 10.1038/s41467-022-34464-6. Nat Commun. 2023. PMID: 36596776 Free PMC article.
Sequence-specific recruitment of heterochromatin protein 1 via interaction with Krüppel-like factor 11, a human transcription factor involved in tumor suppression and metabolic diseases.
Lomberk G, Mathison AJ, Grzenda A, Seo S, DeMars CJ, Ilyas SI, Bonilla-Velez J, Calvo E, Fernandez-Zapico ME, Iovanna J, Buttar NS, Urrutia R. Lomberk G, et al. Among authors: mathison aj. J Biol Chem. 2012 Apr 13;287(16):13026-39. doi: 10.1074/jbc.M112.342634. Epub 2012 Feb 8. J Biol Chem. 2012. PMID: 22318730 Free PMC article.
Functional validation reveals the novel missense V419L variant in TGFBR2 associated with Loeys-Dietz syndrome (LDS) impairs canonical TGF-β signaling.
Cousin MA, Zimmermann MT, Mathison AJ, Blackburn PR, Boczek NJ, Oliver GR, Lomberk GA, Urrutia RA, Deyle DR, Klee EW. Cousin MA, et al. Among authors: mathison aj. Cold Spring Harb Mol Case Stud. 2017 Jul 5;3(4):a001727. doi: 10.1101/mcs.a001727. Print 2017 Jul. Cold Spring Harb Mol Case Stud. 2017. PMID: 28679693 Free PMC article.
Distinct epigenetic landscapes underlie the pathobiology of pancreatic cancer subtypes.
Lomberk G, Blum Y, Nicolle R, Nair A, Gaonkar KS, Marisa L, Mathison A, Sun Z, Yan H, Elarouci N, Armenoult L, Ayadi M, Ordog T, Lee JH, Oliver G, Klee E, Moutardier V, Gayet O, Bian B, Duconseil P, Gilabert M, Bigonnet M, Garcia S, Turrini O, Delpero JR, Giovannini M, Grandval P, Gasmi M, Secq V, De Reyniès A, Dusetti N, Iovanna J, Urrutia R. Lomberk G, et al. Nat Commun. 2018 May 17;9(1):1978. doi: 10.1038/s41467-018-04383-6. Nat Commun. 2018. PMID: 29773832 Free PMC article.
Aurora kinase B-phosphorylated HP1α functions in chromosomal instability.
Williams MM, Mathison AJ, Christensen T, Greipp PT, Knutson DL, Klee EW, Zimmermann MT, Iovanna J, Lomberk GA, Urrutia RA. Williams MM, et al. Among authors: mathison aj. Cell Cycle. 2019 Jun;18(12):1407-1421. doi: 10.1080/15384101.2019.1618126. Epub 2019 May 26. Cell Cycle. 2019. PMID: 31130069 Free PMC article.
70 results