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The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis.
Han L, Wu Y, Fang K, Sweeney S, Roesner UK, Parrish M, Patel K, Walter T, Piermattei J, Trimboli A, Lefler J, Timmers CD, Yu XZ, Jin VX, Zimmermann MT, Mathison AJ, Urrutia R, Ostrowski MC, Leone G. Han L, et al. Among authors: zimmermann mt. Nat Commun. 2023 Jan 3;14(1):1. doi: 10.1038/s41467-022-34464-6. Nat Commun. 2023. PMID: 36596776 Free PMC article.
Functional validation reveals the novel missense V419L variant in TGFBR2 associated with Loeys-Dietz syndrome (LDS) impairs canonical TGF-β signaling.
Cousin MA, Zimmermann MT, Mathison AJ, Blackburn PR, Boczek NJ, Oliver GR, Lomberk GA, Urrutia RA, Deyle DR, Klee EW. Cousin MA, et al. Among authors: zimmermann mt. Cold Spring Harb Mol Case Stud. 2017 Jul 5;3(4):a001727. doi: 10.1101/mcs.a001727. Print 2017 Jul. Cold Spring Harb Mol Case Stud. 2017. PMID: 28679693 Free PMC article.
Aurora kinase B-phosphorylated HP1α functions in chromosomal instability.
Williams MM, Mathison AJ, Christensen T, Greipp PT, Knutson DL, Klee EW, Zimmermann MT, Iovanna J, Lomberk GA, Urrutia RA. Williams MM, et al. Among authors: zimmermann mt. Cell Cycle. 2019 Jun;18(12):1407-1421. doi: 10.1080/15384101.2019.1618126. Epub 2019 May 26. Cell Cycle. 2019. PMID: 31130069 Free PMC article.
Molecular mechanics and dynamic simulations of well-known Kabuki syndrome-associated KDM6A variants reveal putative mechanisms of dysfunction.
Chi YI, Stodola TJ, De Assuncao TM, Leverence EN, Tripathi S, Dsouza NR, Mathison AJ, Basel DG, Volkman BF, Smith BC, Lomberk G, Zimmermann MT, Urrutia R. Chi YI, et al. Among authors: zimmermann mt. Orphanet J Rare Dis. 2021 Feb 5;16(1):66. doi: 10.1186/s13023-021-01692-w. Orphanet J Rare Dis. 2021. PMID: 33546721 Free PMC article.
136 results