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Reply to Root-Bernstein: Increasing complexity allows for the pervasiveness of low-complexity entities and is not anthropocentric.
Wong ML, Bartlett S, Cleland CE, Demarest H, Cleaves HJ 2nd, Prabhu A, Lunine JI, Hazen RM. Wong ML, et al. Among authors: demarest h. Proc Natl Acad Sci U S A. 2024 Aug 20;121(34):e2406598121. doi: 10.1073/pnas.2406598121. Epub 2024 Aug 12. Proc Natl Acad Sci U S A. 2024. PMID: 39133837 Free PMC article. No abstract available.
On the roles of function and selection in evolving systems.
Wong ML, Cleland CE, Arend D Jr, Bartlett S, Cleaves HJ 2nd, Demarest H, Prabhu A, Lunine JI, Hazen RM. Wong ML, et al. Among authors: demarest h. Proc Natl Acad Sci U S A. 2023 Oct 24;120(43):e2310223120. doi: 10.1073/pnas.2310223120. Epub 2023 Oct 16. Proc Natl Acad Sci U S A. 2023. PMID: 37844243 Free PMC article.
Randomized, open-label, phase 2a study to evaluate the contribution of artefenomel to the clinical and parasiticidal activity of artefenomel plus ferroquine in African patients with uncomplicated Plasmodium falciparum malaria.
Gansane A, Lingani M, Yeka A, Nahum A, Bouyou-Akotet M, Mombo-Ngoma G, Kaguthi G, Barceló C, Laurijssens B, Cantalloube C, Macintyre F, Djeriou E, Jessel A, Bejuit R, Demarest H, Marrast AC, Debe S, Tinto H, Kibuuka A, Nahum D, Mawili-Mboumba DP, Zoleko-Manego R, Mugenya I, Olewe F, Duparc S, Ogutu B. Gansane A, et al. Among authors: demarest h. Malar J. 2023 Jan 3;22(1):2. doi: 10.1186/s12936-022-04420-2. Malar J. 2023. PMID: 36597076 Free PMC article. Clinical Trial.
A randomised, double-blind clinical phase II trial of the efficacy, safety, tolerability and pharmacokinetics of a single dose combination treatment with artefenomel and piperaquine in adults and children with uncomplicated Plasmodium falciparum malaria.
Macintyre F, Adoke Y, Tiono AB, Duong TT, Mombo-Ngoma G, Bouyou-Akotet M, Tinto H, Bassat Q, Issifou S, Adamy M, Demarest H, Duparc S, Leroy D, Laurijssens BE, Biguenet S, Kibuuka A, Tshefu AK, Smith M, Foster C, Leipoldt I, Kremsner PG, Phuc BQ, Ouedraogo A, Ramharter M; OZ-Piperaquine Study Group. Macintyre F, et al. Among authors: demarest h. BMC Med. 2017 Oct 9;15(1):181. doi: 10.1186/s12916-017-0940-3. BMC Med. 2017. PMID: 28988541 Free PMC article. Clinical Trial.
Effects of extended-release niacin with laropiprant in high-risk patients.
HPS2-THRIVE Collaborative Group; Landray MJ, Haynes R, Hopewell JC, Parish S, Aung T, Tomson J, Wallendszus K, Craig M, Jiang L, Collins R, Armitage J. HPS2-THRIVE Collaborative Group, et al. N Engl J Med. 2014 Jul 17;371(3):203-12. doi: 10.1056/NEJMoa1300955. N Engl J Med. 2014. PMID: 25014686 Free article. Clinical Trial.