Induction of apoptosis in macrophages by Pseudomonas aeruginosa azurin: tumour-suppressor protein p53 and reactive oxygen species, but not redox activity, as critical elements in cytotoxicity.
Goto M, Yamada T, Kimbara K, Horner J, Newcomb M, Gupta TK, Chakrabarty AM.
Goto M, et al. Among authors: yamada t.
Mol Microbiol. 2003 Jan;47(2):549-59. doi: 10.1046/j.1365-2958.2003.03317.x.
Mol Microbiol. 2003.
PMID: 12519204
Free article.
We reported recently that purified azurin demonstrates cytotoxicity to macrophages by forming a complex with the tumour-suppressor protein p53, thereby stabilizing it and enhancing its function as an inducer of proapoptotic activity (Yamada, T., Goto, M., Punj, V., …
We reported recently that purified azurin demonstrates cytotoxicity to macrophages by forming a complex with the tumour-suppressor protein p …