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Fragment-to-Lead Medicinal Chemistry Publications in 2021.
Walsh L, Erlanson DA, de Esch IJP, Jahnke W, Woodhead A, Wren E. Walsh L, et al. Among authors: jahnke w. J Med Chem. 2023 Jan 26;66(2):1137-1156. doi: 10.1021/acs.jmedchem.2c01827. Epub 2023 Jan 9. J Med Chem. 2023. PMID: 36622056 Review.
Op18/stathmin caps a kinked protofilament-like tubulin tetramer.
Steinmetz MO, Kammerer RA, Jahnke W, Goldie KN, Lustig A, van Oostrum J. Steinmetz MO, et al. Among authors: jahnke w. EMBO J. 2000 Feb 15;19(4):572-80. doi: 10.1093/emboj/19.4.572. EMBO J. 2000. PMID: 10675326 Free PMC article.
The high-resolution solution structure of epothilone A bound to tubulin: an understanding of the structure-activity relationships for a powerful class of antitumor agents.
Carlomagno T, Blommers MJ, Meiler J, Jahnke W, Schupp T, Petersen F, Schinzer D, Altmann KH, Griesinger C. Carlomagno T, et al. Among authors: jahnke w. Angew Chem Int Ed Engl. 2003 Jun 6;42(22):2511-5. doi: 10.1002/anie.200351276. Angew Chem Int Ed Engl. 2003. PMID: 12800173 No abstract available.
98 results