Reynolds VL - Search Results

1

Discovery, development, and clinical proof of mechanism of LY3463251, a long-acting GDF15 receptor agonist.

Benichou O, Coskun T, Gonciarz MD, Garhyan P, Adams AC, Du Y, Dunbar JD, Martin JA, Mather KJ, Pickard RT, Reynolds VL, Robins DA, Zvada SP, Emmerson PJ. Benichou O, et al. Among authors: reynolds vl. Cell Metab. 2023 Feb 7;35(2):274-286.e10. doi: 10.1016/j.cmet.2022.12.011. Epub 2023 Jan 10. Cell Metab. 2023. PMID: 36630958 Free article.

2

LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys.

Adams AC, Halstead CA, Hansen BC, Irizarry AR, Martin JA, Myers SR, Reynolds VL, Smith HW, Wroblewski VJ, Kharitonenkov A. Adams AC, et al. Among authors: reynolds vl. PLoS One. 2013 Jun 18;8(6):e65763. doi: 10.1371/journal.pone.0065763. Print 2013. PLoS One. 2013. PMID: 23823755 Free PMC article.

3

Neoplastic and non-neoplastic changes in F-344 rats treated with Naveglitazar, a gamma-dominant PPAR alpha/gamma agonist.

Long GG, Reynolds VL, Dochterman LW, Ryan TE. Long GG, et al. Among authors: reynolds vl. Toxicol Pathol. 2009 Oct;37(6):741-53. doi: 10.1177/0192623309343775. Epub 2009 Aug 21. Toxicol Pathol. 2009. PMID: 19700659

4

Imidazopyridine and Pyrazolopiperidine Derivatives as Novel Inhibitors of Serine Palmitoyl Transferase.

Genin MJ, Gonzalez Valcarcel IC, Holloway WG, Lamar J, Mosior M, Hawkins E, Estridge T, Weidner J, Seng T, Yurek D, Adams LA, Weller J, Reynolds VL, Brozinick JT. Genin MJ, et al. Among authors: reynolds vl. J Med Chem. 2016 Jun 23;59(12):5904-10. doi: 10.1021/acs.jmedchem.5b01851. Epub 2016 Jun 6. J Med Chem. 2016. PMID: 27213958

5

Applications of emerging technologies in toxicology and safety assessment.

Reynolds VL. Reynolds VL. Int J Toxicol. 2005 May-Jun;24(3):135-7. doi: 10.1080/10915810590948280. Int J Toxicol. 2005. PMID: 16040564 Review.

6

Nonclinical safety assessment of epigenetic modulatory drugs: Current status and industry perspective.

Reynolds VL, Butler P, Abernathy MM, Aschenbrenner L, Best DD, Blank J, Crosby M, Custer L, Escobar PA, Kolaja K, Moggs J, Shuey D, Snyder C, Van Vleet T, Zhou J, Hart TK. Reynolds VL, et al. Regul Toxicol Pharmacol. 2020 Nov;117:104746. doi: 10.1016/j.yrtph.2020.104746. Epub 2020 Sep 8. Regul Toxicol Pharmacol. 2020. PMID: 32911461

7

Assessing the toxicological significance of ejaculatory plugs as a clinical observation in rat toxicology studies: CNS-mediated increases in plug production vs. gustatory-mediated decreases in plug consumption.

Reynolds VL, Stump DG, Holson JF. Reynolds VL, et al. Reprod Toxicol. 2010 Jun;29(3):271-8. doi: 10.1016/j.reprotox.2010.02.003. Epub 2010 Feb 23. Reprod Toxicol. 2010. PMID: 20184952 Review.

8

Urothelial carcinogenesis in the urinary bladder of rats treated with naveglitazar, a gamma-dominant PPAR alpha/gamma agonist: lack of evidence for urolithiasis as an inciting event.

Long GG, Reynolds VL, Lopez-Martinez A, Ryan TE, White SL, Eldridge SR. Long GG, et al. Among authors: reynolds vl. Toxicol Pathol. 2008 Feb;36(2):218-31. doi: 10.1177/0192623307311757. Toxicol Pathol. 2008. PMID: 18474944

9

An inhalation reproductive toxicity study of octamethylcyclotetrasiloxane (D4) in female rats using multiple and single day exposure regimens.

Meeks RG, Stump DG, Siddiqui WH, Holson JF, Plotzke KP, Reynolds VL. Meeks RG, et al. Among authors: reynolds vl. Reprod Toxicol. 2007 Feb;23(2):192-201. doi: 10.1016/j.reprotox.2006.12.005. Epub 2007 Jan 3. Reprod Toxicol. 2007. PMID: 17254748

10

A two-generation reproductive toxicity study of decamethylcyclopentasiloxane (D5) in rats exposed by whole-body vapor inhalation.

Siddiqui WH, Stump DG, Reynolds VL, Plotzke KP, Holson JF, Meeks RG. Siddiqui WH, et al. Among authors: reynolds vl. Reprod Toxicol. 2007 Feb;23(2):216-25. doi: 10.1016/j.reprotox.2006.11.006. Epub 2006 Nov 18. Reprod Toxicol. 2007. PMID: 17175135

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