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Priming with very low-affinity peptide ligands gives rise to CD8(+) T-cell effectors with enhanced function but with greater susceptibility to transforming growth factor (TGF)β-mediated suppression.
O'Sullivan JA, Zloza A, Kohlhapp FJ, Moore TV, Lacek AT, Dulin NO, Guevara-Patiño JA. O'Sullivan JA, et al. Among authors: moore tv. Cancer Immunol Immunother. 2011 Nov;60(11):1543-51. doi: 10.1007/s00262-011-1043-1. Epub 2011 Jun 17. Cancer Immunol Immunother. 2011. PMID: 21681376 Free PMC article.
NKG2D signaling on CD8⁺ T cells represses T-bet and rescues CD4-unhelped CD8⁺ T cell memory recall but not effector responses.
Zloza A, Kohlhapp FJ, Lyons GE, Schenkel JM, Moore TV, Lacek AT, O'Sullivan JA, Varanasi V, Williams JW, Jagoda MC, Bellavance EC, Marzo AL, Thomas PG, Zafirova B, Polić B, Al-Harthi L, Sperling AI, Guevara-Patiño JA. Zloza A, et al. Among authors: moore tv. Nat Med. 2012 Feb 26;18(3):422-8. doi: 10.1038/nm.2683. Nat Med. 2012. PMID: 22366950 Free PMC article.
Antigen recognition and T-cell biology.
Nishimura MI, Roszkowski JJ, Moore TV, Brasic N, McKee MD, Clay TM. Nishimura MI, et al. Among authors: moore tv. Cancer Treat Res. 2005;123:37-59. doi: 10.1007/0-387-27545-2_2. Cancer Treat Res. 2005. PMID: 16211865 Review.
30 results