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The NLRP1 and CARD8 inflammasomes detect reductive stress.
Wang Q, Hsiao JC, Yardeny N, Huang HC, O'Mara CM, Orth-He EL, Ball DP, Zhang Z, Bachovchin DA. Wang Q, et al. Among authors: o mara cm. Cell Rep. 2023 Jan 31;42(1):111966. doi: 10.1016/j.celrep.2022.111966. Epub 2023 Jan 16. Cell Rep. 2023. PMID: 36649710 Free PMC article.
Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation.
Orth-He EL, Huang HC, Rao SD, Wang Q, Chen Q, O'Mara CM, Chui AJ, Saoi M, Griswold AR, Bhattacharjee A, Ball DP, Cross JR, Bachovchin DA. Orth-He EL, et al. Among authors: o mara cm. Cell Rep. 2023 Jan 31;42(1):111965. doi: 10.1016/j.celrep.2022.111965. Epub 2023 Jan 16. Cell Rep. 2023. PMID: 36649711 Free PMC article.