Staby L - Search Results

1

Stereochemistry in the disorder-order continuum of protein interactions.

Newcombe EA, Due AD, Sottini A, Elkjær S, Theisen FF, Fernandes CB, Staby L, Delaforge E, Bartling CRO, Brakti I, Bugge K, Schuler B, Skriver K, Olsen JG, Kragelund BB. Newcombe EA, et al. Among authors: staby l. Nature. 2024 Dec;636(8043):762-768. doi: 10.1038/s41586-024-08271-6. Epub 2024 Nov 27. Nature. 2024. PMID: 39604735 Free PMC article.

2

Evolutionary fine-tuning of residual helix structure in disordered proteins manifests in complex structure and lifetime.

Elkjær S, Due AD, Christensen LF, Theisen FF, Staby L, Kragelund BB, Skriver K. Elkjær S, et al. Among authors: staby l. Commun Biol. 2023 Jan 18;6(1):63. doi: 10.1038/s42003-023-04445-6. Commun Biol. 2023. PMID: 36653471 Free PMC article.

3

A glutamine-based single α-helix scaffold to target globular proteins.

Escobedo A, Piccirillo J, Aranda J, Diercks T, Mateos B, Garcia-Cabau C, Sánchez-Navarro M, Topal B, Biesaga M, Staby L, Kragelund BB, García J, Millet O, Orozco M, Coles M, Crehuet R, Salvatella X. Escobedo A, et al. Among authors: staby l. Nat Commun. 2022 Nov 18;13(1):7073. doi: 10.1038/s41467-022-34793-6. Nat Commun. 2022. PMID: 36400768 Free PMC article.

4

αα-hub coregulator structure and flexibility determine transcription factor binding and selection in regulatory interactomes.

Friis Theisen F, Salladini E, Davidsen R, Jo Rasmussen C, Staby L, Kragelund BB, Skriver K. Friis Theisen F, et al. Among authors: staby l. J Biol Chem. 2022 Jun;298(6):101963. doi: 10.1016/j.jbc.2022.101963. Epub 2022 Apr 20. J Biol Chem. 2022. PMID: 35452682 Free PMC article.

5

Flanking Disorder of the Folded αα-Hub Domain from Radical Induced Cell Death1 Affects Transcription Factor Binding by Ensemble Redistribution.

Staby L, Due AD, Kunze MBA, Jørgensen MLM, Skriver K, Kragelund BB. Staby L, et al. J Mol Biol. 2021 Dec 3;433(24):167320. doi: 10.1016/j.jmb.2021.167320. Epub 2021 Oct 21. J Mol Biol. 2021. PMID: 34687712

6

Quantification of Conformational Entropy Unravels Effect of Disordered Flanking Region in Coupled Folding and Binding.

Theisen FF, Staby L, Tidemand FG, O'Shea C, Prestel A, Willemoës M, Kragelund BB, Skriver K. Theisen FF, et al. Among authors: staby l. J Am Chem Soc. 2021 Sep 15;143(36):14540-14550. doi: 10.1021/jacs.1c04214. Epub 2021 Sep 2. J Am Chem Soc. 2021. PMID: 34473923 Free article.

7

Connecting the αα-hubs: same fold, disordered ligands, new functions.

Staby L, Bugge K, Falbe-Hansen RG, Salladini E, Skriver K, Kragelund BB. Staby L, et al. Cell Commun Signal. 2021 Jan 6;19(1):2. doi: 10.1186/s12964-020-00686-8. Cell Commun Signal. 2021. PMID: 33407551 Free PMC article.

8

αα-Hub domains and intrinsically disordered proteins: A decisive combo.

Bugge K, Staby L, Salladini E, Falbe-Hansen RG, Kragelund BB, Skriver K. Bugge K, et al. Among authors: staby l. J Biol Chem. 2021 Jan-Jun;296:100226. doi: 10.1074/jbc.REV120.012928. Epub 2020 Dec 29. J Biol Chem. 2021. PMID: 33361159 Free PMC article. Review.

9

Disorder in a two-domain neuronal Ca²⁺-binding protein regulates domain stability and dynamics using ligand mimicry.

Staby L, Kemplen KR, Stein A, Ploug M, Clarke J, Skriver K, Heidarsson PO, Kragelund BB. Staby L, et al. Cell Mol Life Sci. 2021 Mar;78(5):2263-2278. doi: 10.1007/s00018-020-03639-z. Epub 2020 Sep 16. Cell Mol Life Sci. 2021. PMID: 32936312 Free PMC article.

10

Evolutionary conservation of the intrinsic disorder-based Radical-Induced Cell Death1 hub interactome.

Christensen LF, Staby L, Bugge K, O'Shea C, Kragelund BB, Skriver K. Christensen LF, et al. Among authors: staby l. Sci Rep. 2019 Dec 12;9(1):18927. doi: 10.1038/s41598-019-55385-3. Sci Rep. 2019. PMID: 31831797 Free PMC article.

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