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Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction.
Miyazawa K, Ito K, Ito M, Zou Z, Kubota M, Nomura S, Matsunaga H, Koyama S, Ieki H, Akiyama M, Koike Y, Kurosawa R, Yoshida H, Ozaki K, Onouchi Y; BioBank Japan Project; Takahashi A, Matsuda K, Murakami Y, Aburatani H, Kubo M, Momozawa Y, Terao C, Oki S, Akazawa H, Kamatani Y, Komuro I. Miyazawa K, et al. Among authors: ito k, ito m. Nat Genet. 2023 Feb;55(2):187-197. doi: 10.1038/s41588-022-01284-9. Epub 2023 Jan 19. Nat Genet. 2023. PMID: 36653681 Free PMC article.
Complement C1q-induced activation of β-catenin signalling causes hypertensive arterial remodelling.
Sumida T, Naito AT, Nomura S, Nakagawa A, Higo T, Hashimoto A, Okada K, Sakai T, Ito M, Yamaguchi T, Oka T, Akazawa H, Lee JK, Minamino T, Offermanns S, Noda T, Botto M, Kobayashi Y, Morita H, Manabe I, Nagai T, Shiojima I, Komuro I. Sumida T, et al. Among authors: ito m. Nat Commun. 2015 Feb 26;6:6241. doi: 10.1038/ncomms7241. Nat Commun. 2015. PMID: 25716000 Free PMC article.
Wnt/β-Catenin Signaling Contributes to Skeletal Myopathy in Heart Failure via Direct Interaction With Forkhead Box O.
Okada K, Naito AT, Higo T, Nakagawa A, Shibamoto M, Sakai T, Hashimoto A, Kuramoto Y, Sumida T, Nomura S, Ito M, Yamaguchi T, Oka T, Akazawa H, Lee JK, Morimoto S, Sakata Y, Shiojima I, Komuro I. Okada K, et al. Among authors: ito m. Circ Heart Fail. 2015 Jul;8(4):799-808. doi: 10.1161/CIRCHEARTFAILURE.114.001958. Epub 2015 Jun 2. Circ Heart Fail. 2015. PMID: 26038536
DNA single-strand break-induced DNA damage response causes heart failure.
Higo T, Naito AT, Sumida T, Shibamoto M, Okada K, Nomura S, Nakagawa A, Yamaguchi T, Sakai T, Hashimoto A, Kuramoto Y, Ito M, Hikoso S, Akazawa H, Lee JK, Shiojima I, McKinnon PJ, Sakata Y, Komuro I. Higo T, et al. Among authors: ito m. Nat Commun. 2017 Apr 24;8:15104. doi: 10.1038/ncomms15104. Nat Commun. 2017. PMID: 28436431 Free PMC article.
Genetic basis of cardiomyopathy and the genotypes involved in prognosis and left ventricular reverse remodeling.
Tobita T, Nomura S, Fujita T, Morita H, Asano Y, Onoue K, Ito M, Imai Y, Suzuki A, Ko T, Satoh M, Fujita K, Naito AT, Furutani Y, Toko H, Harada M, Amiya E, Hatano M, Takimoto E, Shiga T, Nakanishi T, Sakata Y, Ono M, Saito Y, Takashima S, Hagiwara N, Aburatani H, Komuro I. Tobita T, et al. Among authors: ito m. Sci Rep. 2018 Jan 31;8(1):1998. doi: 10.1038/s41598-018-20114-9. Sci Rep. 2018. PMID: 29386531 Free PMC article.
Cardiomyopathy with LMNA Mutation.
Ito M, Nomura S. Ito M, et al. Int Heart J. 2018;59(3):462-464. doi: 10.1536/ihj.18-214. Int Heart J. 2018. PMID: 29848893 Free article. No abstract available.
Phenotypic Screening Using Patient-Derived Induced Pluripotent Stem Cells Identified Pyr3 as a Candidate Compound for the Treatment of Infantile Hypertrophic Cardiomyopathy.
Sakai T, Naito AT, Kuramoto Y, Ito M, Okada K, Higo T, Nakagawa A, Shibamoto M, Yamaguchi T, Sumida T, Nomura S, Umezawa A, Miyagawa S, Sawa Y, Morita H, Lee JK, Shiojima I, Sakata Y, Komuro I. Sakai T, et al. Among authors: ito m. Int Heart J. 2018 Sep 26;59(5):1096-1105. doi: 10.1536/ihj.17-730. Epub 2018 Aug 11. Int Heart J. 2018. PMID: 30101858 Free article.
Cardiomyocyte gene programs encoding morphological and functional signatures in cardiac hypertrophy and failure.
Nomura S, Satoh M, Fujita T, Higo T, Sumida T, Ko T, Yamaguchi T, Tobita T, Naito AT, Ito M, Fujita K, Harada M, Toko H, Kobayashi Y, Ito K, Takimoto E, Akazawa H, Morita H, Aburatani H, Komuro I. Nomura S, et al. Among authors: ito k, ito m. Nat Commun. 2018 Oct 30;9(1):4435. doi: 10.1038/s41467-018-06639-7. Nat Commun. 2018. PMID: 30375404 Free PMC article.
Discovery of a Small Molecule to Increase Cardiomyocytes and Protect the Heart After Ischemic Injury.
Hara H, Takeda N, Kondo M, Kubota M, Saito T, Maruyama J, Fujiwara T, Maemura S, Ito M, Naito AT, Harada M, Toko H, Nomura S, Kumagai H, Ikeda Y, Ueno H, Takimoto E, Akazawa H, Morita H, Aburatani H, Hata Y, Uchiyama M, Komuro I. Hara H, et al. Among authors: ito m. JACC Basic Transl Sci. 2018 Nov 12;3(5):639-653. doi: 10.1016/j.jacbts.2018.07.005. eCollection 2018 Oct. JACC Basic Transl Sci. 2018. PMID: 30456335 Free PMC article.
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