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Chemical synthesis of 7-oxygenated 12α-hydroxy steroid derivatives to enable the biochemical characterization of cytochrome P450 8B1, the oxysterol 12α-hydroxylase enzyme implicated in cardiovascular health and obesity.
Offei SD, Arman HD, Baig MO, Chavez LS, Paladini CA, Yoshimoto FK. Offei SD, et al. Among authors: baig mo. Steroids. 2018 Dec;140:185-195. doi: 10.1016/j.steroids.2018.10.010. Epub 2018 Nov 3. Steroids. 2018. PMID: 30399365 Free PMC article.