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AtomNet-Aided OTUD7B Inhibitor Discovery and Validation.
Chen J, Bolhuis DL, Laggner C, Kong D, Yu L, Wang X, Emanuele MJ, Brown NG, Liu P. Chen J, et al. Among authors: wang x. Cancers (Basel). 2023 Jan 14;15(2):517. doi: 10.3390/cancers15020517. Cancers (Basel). 2023. PMID: 36672466 Free PMC article.
The Emerging Role of TYRO3 as a Therapeutic Target in Cancer.
Smart SK, Vasileiadi E, Wang X, DeRyckere D, Graham DK. Smart SK, et al. Among authors: wang x. Cancers (Basel). 2018 Nov 29;10(12):474. doi: 10.3390/cancers10120474. Cancers (Basel). 2018. PMID: 30501104 Free PMC article. Review.
MERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression.
Jiang Y, Zhang Y, Leung JY, Fan C, Popov KI, Su S, Qian J, Wang X, Holtzhausen A, Ubil E, Xiang Y, Davis I, Dokholyan NV, Wu G, Perou CM, Kim WY, Earp HS, Liu P. Jiang Y, et al. Among authors: wang x. Nat Commun. 2019 Apr 3;10(1):1515. doi: 10.1038/s41467-019-09233-7. Nat Commun. 2019. PMID: 30944303 Free PMC article.
Discovery of Novel Macrocyclic MERTK/AXL Dual Inhibitors.
Kong D, Tian Q, Chen Z, Zheng H, Stashko MA, Yan D, Earp HS, Frye SV, DeRyckere D, Kireev D, Graham DK, Wang X. Kong D, et al. Among authors: wang x. J Med Chem. 2024 Apr 11;67(7):5866-5882. doi: 10.1021/acs.jmedchem.4c00148. Epub 2024 Mar 31. J Med Chem. 2024. PMID: 38556760
MERTK Is a Potential Therapeutic Target in Ewing Sarcoma.
Smart SK, Yeung TY, Santos MO, McSwain LF, Wang X, Frye SV, Earp HS 3rd, DeRyckere D, Graham DK. Smart SK, et al. Among authors: wang x. Cancers (Basel). 2024 Aug 12;16(16):2831. doi: 10.3390/cancers16162831. Cancers (Basel). 2024. PMID: 39199601 Free PMC article.
2'3'-cGAMP interactome identifies 2'3'-cGAMP/Rab18/FosB signaling in cell migration control independent of innate immunity.
Deng Y, Hahn Q, Yu L, Zhu Z, Boyer JA, Wang J, Kong D, Carey LM, Hepperla AJ, Simon JM, Temple B, Zhang Z, Zhang Y, Santos C, Frank JE, Herring LE, Wang X, Dokholyan NV, Campbell SL, Baldwin AS, Damania B, Zhang Q, Liu P. Deng Y, et al. Among authors: wang x, wang j. Sci Adv. 2024 Oct 18;10(42):eado7024. doi: 10.1126/sciadv.ado7024. Epub 2024 Oct 16. Sci Adv. 2024. PMID: 39413198 Free PMC article.
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