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3D blood-brain barrier-organoids as a model for Lyme neuroborreliosis highlighting genospecies dependent organotropism.
Adams Y, Clausen AS, Jensen PØ, Lager M, Wilhelmsson P, Henningson AJ, Lindgren PE, Faurholt-Jepsen D, Mens H, Kraiczy P, Kragh KN, Bjarnsholt T, Kjaer A, Lebech AM, Jensen AR. Adams Y, et al. Among authors: bjarnsholt t. iScience. 2022 Dec 19;26(1):105838. doi: 10.1016/j.isci.2022.105838. eCollection 2023 Jan 20. iScience. 2022. PMID: 36686395 Free PMC article.
Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa.
Jensen PØ, Bjarnsholt T, Phipps R, Rasmussen TB, Calum H, Christoffersen L, Moser C, Williams P, Pressler T, Givskov M, Høiby N. Jensen PØ, et al. Among authors: bjarnsholt t. Microbiology (Reading). 2007 May;153(Pt 5):1329-1338. doi: 10.1099/mic.0.2006/003863-0. Microbiology (Reading). 2007. PMID: 17464047 Free article.
Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes.
Van Gennip M, Christensen LD, Alhede M, Phipps R, Jensen PØ, Christophersen L, Pamp SJ, Moser C, Mikkelsen PJ, Koh AY, Tolker-Nielsen T, Pier GB, Høiby N, Givskov M, Bjarnsholt T. Van Gennip M, et al. Among authors: bjarnsholt t. APMIS. 2009 Jul;117(7):537-46. doi: 10.1111/j.1600-0463.2009.02466.x. APMIS. 2009. PMID: 19594494 Free PMC article.
276 results