Guzik H - Search Results

1

Antiulcer agents. 2. Gastric antisecretory, cytoprotective, and metabolic properties of substituted imidazo[1,2-a]pyridines and analogues.

Kaminski JJ, Hilbert JM, Pramanik BN, Solomon DM, Conn DJ, Rizvi RK, Elliott AJ, Guzik H, Lovey RG, Domalski MS, et al. Kaminski JJ, et al. Among authors: guzik h. J Med Chem. 1987 Nov;30(11):2031-46. doi: 10.1021/jm00394a018. J Med Chem. 1987. PMID: 3669011

2

Isobenzofurans as conformationally constrained miconazole analogues with improved antifungal potency.

Lovey RG, Elliott AJ, Kaminski JJ, Loebenberg D, Parmegiani RM, Rane DF, Girijavallabhan VM, Pike RE, Guzik H, Antonacci B, et al. Lovey RG, et al. Among authors: guzik h. J Med Chem. 1992 Oct 30;35(22):4221-9. doi: 10.1021/jm00100a030. J Med Chem. 1992. PMID: 1433223

3

Antiulcer agents. 4. Conformational considerations and the antiulcer activity of substituted imidazo[1,2-a]pyridines and related analogues.

Kaminski JJ, Puchalski C, Solomon DM, Rizvi RK, Conn DJ, Elliott AJ, Lovey RG, Guzik H, Chiu PJ, Long JF, et al. Kaminski JJ, et al. Among authors: guzik h. J Med Chem. 1989 Aug;32(8):1686-700. doi: 10.1021/jm00128a005. J Med Chem. 1989. PMID: 2754693

4

Antiulcer agents. 1. Gastric antisecretory and cytoprotective properties of substituted imidazo[1,2-a]pyridines.

Kaminski JJ, Bristol JA, Puchalski C, Lovey RG, Elliott AJ, Guzik H, Solomon DM, Conn DJ, Domalski MS, Wong SC, et al. Kaminski JJ, et al. Among authors: guzik h. J Med Chem. 1985 Jul;28(7):876-92. doi: 10.1021/jm00145a006. J Med Chem. 1985. PMID: 4009611

5

Synthesis of some 5-phenylhexahydroazepino[4,5-b]indoles as potential neuroleptic agents.

Elliott AJ, Gold EH, Guzik H. Elliott AJ, et al. Among authors: guzik h. J Med Chem. 1980 Nov;23(11):1268-9. doi: 10.1021/jm00185a028. J Med Chem. 1980. PMID: 6109026

6

Synthesis and antifungal activity of the 2,2,5-tetrahydrofuran regioisomers of SCH 51048.

Lovey RG, Saksena AK, Girijavallabhan VM, Blundell P, Guzik H, Loebenberg D, Parmegiani RM, Cacciapuoti A. Lovey RG, et al. Among authors: guzik h. Bioorg Med Chem Lett. 2002 Jul 8;12(13):1739-42. doi: 10.1016/s0960-894x(02)00282-2. Bioorg Med Chem Lett. 2002. PMID: 12067550

7

Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas.

McBriar MD, Guzik H, Shapiro S, Paruchova J, Xu R, Palani A, Clader JW, Cox K, Greenlee WJ, Hawes BE, Kowalski TJ, O'neill K, Spar BD, Weig B, Weston DJ, Farley C, Cook J. McBriar MD, et al. Among authors: guzik h. J Med Chem. 2006 Apr 6;49(7):2294-310. doi: 10.1021/jm050886n. J Med Chem. 2006. PMID: 16570926

8

Optimization of purine based PDE1/PDE5 inhibitors to a potent and selective PDE5 inhibitor for the treatment of male ED.

Boyle CD, Xu R, Asberom T, Chackalamannil S, Clader JW, Greenlee WJ, Guzik H, Hu Y, Hu Z, Lankin CM, Pissarnitski DA, Stamford AW, Wang Y, Skell J, Kurowski S, Vemulapalli S, Palamanda J, Chintala M, Wu P, Myers J, Wang P. Boyle CD, et al. Among authors: guzik h. Bioorg Med Chem Lett. 2005 May 2;15(9):2365-9. doi: 10.1016/j.bmcl.2005.02.083. Bioorg Med Chem Lett. 2005. PMID: 15837326

9

Bicyclic[4.1.0]heptanes as phenyl replacements for melanin concentrating hormone receptor antagonists.

Xu R, Li S, Paruchova J, McBriar MD, Guzik H, Palani A, Clader JW, Cox K, Greenlee WJ, Hawes BE, Kowalski TJ, O'Neill K, Spar BD, Weig B, Weston DJ. Xu R, et al. Among authors: guzik h. Bioorg Med Chem. 2006 May 15;14(10):3285-99. doi: 10.1016/j.bmc.2005.12.046. Epub 2006 Jan 26. Bioorg Med Chem. 2006. PMID: 16442800

10

Discovery of bicycloalkyl urea melanin concentrating hormone receptor antagonists: orally efficacious antiobesity therapeutics.

McBriar MD, Guzik H, Xu R, Paruchova J, Li S, Palani A, Clader JW, Greenlee WJ, Hawes BE, Kowalski TJ, O'Neill K, Spar B, Weig B. McBriar MD, et al. Among authors: guzik h. J Med Chem. 2005 Apr 7;48(7):2274-7. doi: 10.1021/jm049035q. J Med Chem. 2005. PMID: 15801820

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