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CSL324, a granulocyte colony-stimulating factor receptor antagonist, blocks neutrophil migration markers that are upregulated in hidradenitis suppurativa.
Gamell C, Bankovacki A, Scalzo-Inguanti K, Sedgmen B, Alhamdoosh M, Gail E, Turkovic L, Millar C, Johnson L, Wahlsten M, Richter J, Schuster J, Dyson A, Nicolopoulos J, Varigos G, Ng M, Wilson N, Field J, Kern JS, Lindqvist LM. Gamell C, et al. Among authors: kern js. Br J Dermatol. 2023 Apr 20;188(5):636-648. doi: 10.1093/bjd/ljad013. Br J Dermatol. 2023. PMID: 36691791 Clinical Trial.
Randomized controlled trial of omalizumab in treatment-resistant systemic and cutaneous mastocytosis (ROAM).
McComish JS, Slade CA, Buizen L, Paul SK, Chatelier JW, Unglik G, Nicholls KA, Spriggs K, Chan SS, Godsell J, Auyeung P, Tan ZH, DeLuca J, Patel M, Kuek LE, Tran Y, Kern JS, Scardamaglia L, Varigos GA, Juneja S, Grabek JA, Christie M, Mackay GA, Douglass JA. McComish JS, et al. Among authors: kern js. J Allergy Clin Immunol Pract. 2023 Jul;11(7):2248-2250.e3. doi: 10.1016/j.jaip.2023.04.008. Epub 2023 Apr 23. J Allergy Clin Immunol Pract. 2023. PMID: 37088371 Clinical Trial. No abstract available.
Trial protocol for SiroSkin: a randomised double-blind placebo-controlled trial of topical sirolimus in chemoprevention of facial squamous cell carcinomas in solid organ transplant recipients.
Dousset L, Chambers DC, Webster A, Isbel N, Campbell S, Duarte C, Collins L, Damian D, Tseng A, Karlsen E, Ilinsky OV, Brown S, Schaider H, Soyer HP, Ospino DA, Hogarth S, Chong AH, Mar V, McKenzie S, Gin D, Fernandez-Penas P, Kern JS, Loewe K, Roy E, Herschtal A, Khosrotehrani K. Dousset L, et al. Among authors: kern js. Trials. 2024 Nov 22;25(1):789. doi: 10.1186/s13063-024-08619-3. Trials. 2024. PMID: 39578921 Free PMC article.
CXCL17 induces activation of human mast cells via MRGPRX2.
Ding J, Hillig C, White CW, Fernandopulle NA, Anderton H, Kern JS, Menden MP, Mackay GA. Ding J, et al. Among authors: kern js. Allergy. 2024 Jun;79(6):1609-1612. doi: 10.1111/all.16036. Epub 2024 Jan 26. Allergy. 2024. PMID: 38279626 No abstract available.
Study protocol: Australasian Registry of Severe Cutaneous Adverse Reactions (AUS-SCAR).
James F, Goh MSY, Mouhtouris E, Vogrin S, Chua KYL, Holmes NE, Awad A, Copaescu AM, De Luca JF, Zubrinich C, Gin D, Cleland H, Douglas A, Kern JS, Katelaris CH, Thien F, Barnes S, Yun J, Tong W, Smith WB, Carr A, Anderson T, Legg A, Bourke J, Mackay LK, Aung AK, Phillips EJ, Trubiano J. James F, et al. Among authors: kern js. BMJ Open. 2022 Aug 17;12(8):e055906. doi: 10.1136/bmjopen-2021-055906. BMJ Open. 2022. PMID: 35977774 Free PMC article.
The Australasian Registry for Severe Cutaneous Adverse Reactions (AUS-SCAR) - Providing a roadmap for closing the diagnostic, patient, and healthcare gaps for a group of rare drug eruptions.
James F, Goh MS, Vogrin S, Ng I, Douglas AP, Holmes NE, Chua KY, De Luca J, Sharma P, Zubrinich C, Aung AK, Gin D, Lambros B, Baker C, Foley P, Chong AH, Thien F, Fok JS, Su J, Scardamaglia L, Awad A, Tong S, Johnson D, Godsell J, Arasu A, Barnes S, Ojaimi S, Mar A, Yun J, Ange N, Tong WWY, Carr A, Loprete J, Katelaris CH, Slape D, Keat K, West TA, Lee M, Smith W, Hissaria P, Sidhu S, Janson S, Venkatesan S, Davies J, Lane MJ, Redmond AM, Robertson I, Legg A, Fernando S, Boyle T, Li J, Phillips EJ, Cleland H, Kern JS, Trubiano JA. James F, et al. Among authors: kern js. World Allergy Organ J. 2024 Aug 5;17(8):100936. doi: 10.1016/j.waojou.2024.100936. eCollection 2024 Aug. World Allergy Organ J. 2024. PMID: 39211425 Free PMC article.
107 results