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CSL324, a granulocyte colony-stimulating factor receptor antagonist, blocks neutrophil migration markers that are upregulated in hidradenitis suppurativa.
Gamell C, Bankovacki A, Scalzo-Inguanti K, Sedgmen B, Alhamdoosh M, Gail E, Turkovic L, Millar C, Johnson L, Wahlsten M, Richter J, Schuster J, Dyson A, Nicolopoulos J, Varigos G, Ng M, Wilson N, Field J, Kern JS, Lindqvist LM. Gamell C, et al. Among authors: sedgmen b. Br J Dermatol. 2023 Apr 20;188(5):636-648. doi: 10.1093/bjd/ljad013. Br J Dermatol. 2023. PMID: 36691791 Clinical Trial.
Ex vivo restimulation of human PBMC expands a CD3+CD4-CD8- γδ+ T cell population that can confound the evaluation of CD4 and CD8 T cell responses to vaccination.
Sedgmen BJ, Papalia L, Wang L, Dyson AR, McCallum HA, Simson CM, Pearse MJ, Maraskovsky E, Hung D, Eomois PP, Hartel G, Barnden MJ, Rockman SP. Sedgmen BJ, et al. Clin Dev Immunol. 2013;2013:186420. doi: 10.1155/2013/186420. Epub 2013 Aug 26. Clin Dev Immunol. 2013. PMID: 24066003 Free PMC article.
15 results