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Page 1
Successfully Navigating Food and Drug Administration Orphan Drug and Rare Pediatric Disease Designations for AAV9-hPCCA Gene Therapy: The National Institutes of Health Platform Vector Gene Therapy Experience.
Lomash RM, Shchelochkov O, Chandler RJ, Venditti CP, Pariser AR, Ottinger EA; NIH PaVe-GT Team. Lomash RM, et al. Among authors: ottinger ea. Hum Gene Ther. 2023 Mar;34(5-6):217-227. doi: 10.1089/hum.2022.232. Hum Gene Ther. 2023. PMID: 36694456 Free PMC article.
Stabilized trimeric peptide immunogens of the complete HIV-1 gp41 N-heptad repeat and their use as HIV-1 vaccine candidates.
Wu C, Raheem IT, Nahas DD, Citron M, Kim PS, Montefiori DC, Ottinger EA, Hepler RW, Hrin R, Patel SB, Soisson SM, Joyce JG. Wu C, et al. Among authors: ottinger ea. Proc Natl Acad Sci U S A. 2024 May 28;121(22):e2317230121. doi: 10.1073/pnas.2317230121. Epub 2024 May 20. Proc Natl Acad Sci U S A. 2024. PMID: 38768344 Free PMC article.
The Platform Vector Gene Therapies Project: Increasing the Efficiency of Adeno-Associated Virus Gene Therapy Clinical Trial Startup.
Brooks PJ, Ottinger EA, Portero D, Lomash RM, Alimardanov A, Terse P, Xu X, Chandler RJ, Geist Hauserman J, Esposito E, Bönnemann CG, Venditti CP, Austin CP, Pariser A, Lo DC. Brooks PJ, et al. Among authors: ottinger ea. Hum Gene Ther. 2020 Oct;31(19-20):1034-1042. doi: 10.1089/hum.2020.259. Hum Gene Ther. 2020. PMID: 32993373 Free PMC article. No abstract available.
Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene.
Li R, Baskfield A, Lin Y, Beers J, Zou J, Liu C, Jaffré F, Roberts AE, Ottinger EA, Kontaridis MI, Zheng W. Li R, et al. Among authors: ottinger ea. Stem Cell Res. 2019 Jan;34:101374. doi: 10.1016/j.scr.2018.101374. Epub 2018 Dec 26. Stem Cell Res. 2019. PMID: 30640061 Free PMC article.
In Vivo Efficacy of VT-1129 against Experimental Cryptococcal Meningitis with the Use of a Loading Dose-Maintenance Dose Administration Strategy.
Wiederhold NP, Xu X, Wang A, Najvar LK, Garvey EP, Ottinger EA, Alimardanov A, Cradock J, Behnke M, Hoekstra WJ, Brand SR, Schotzinger RJ, Jaramillo R, Olivo M, Kirkpatrick WR, Patterson TF. Wiederhold NP, et al. Among authors: ottinger ea. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e01315-18. doi: 10.1128/AAC.01315-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30104280 Free PMC article.
In vitro and in vivo translational models for rare liver diseases.
Haugabook SJ, Ferrer M, Ottinger EA. Haugabook SJ, et al. Among authors: ottinger ea. Biochim Biophys Acta Mol Basis Dis. 2019 May 1;1865(5):1003-1018. doi: 10.1016/j.bbadis.2018.07.029. Epub 2018 Aug 1. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 30075192 Free article. Review.
The Fungal Cyp51 Inhibitor VT-1129 Is Efficacious in an Experimental Model of Cryptococcal Meningitis.
Wiederhold NP, Najvar LK, Garvey EP, Brand SR, Xu X, Ottinger EA, Alimardanov A, Cradock J, Behnke M, Hoekstra WJ, Schotzinger RJ, Jaramillo R, Olivo M, Kirkpatrick WR, Patterson TF. Wiederhold NP, et al. Among authors: ottinger ea. Antimicrob Agents Chemother. 2018 Aug 27;62(9):e01071-18. doi: 10.1128/AAC.01071-18. Print 2018 Sep. Antimicrob Agents Chemother. 2018. PMID: 29987152 Free PMC article.
24 results