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The Transcriptional Response to Lung-Targeting Lipid Nanoparticles in Vivo.
Radmand A, Lokugamage MP, Kim H, Dobrowolski C, Zenhausern R, Loughrey D, Huayamares SG, Hatit MZC, Ni H, Del Cid A, Da Silva Sanchez AJ, Paunovska K, Schrader Echeverri E, Shajii A, Peck H, Santangelo PJ, Dahlman JE. Radmand A, et al. Among authors: santangelo pj. Nano Lett. 2023 Feb 8;23(3):993-1002. doi: 10.1021/acs.nanolett.2c04479. Epub 2023 Jan 26. Nano Lett. 2023. PMID: 36701517 Free PMC article.
A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation.
Paunovska K, Sago CD, Monaco CM, Hudson WH, Castro MG, Rudoltz TG, Kalathoor S, Vanover DA, Santangelo PJ, Ahmed R, Bryksin AV, Dahlman JE. Paunovska K, et al. Among authors: santangelo pj. Nano Lett. 2018 Mar 14;18(3):2148-2157. doi: 10.1021/acs.nanolett.8b00432. Epub 2018 Mar 5. Nano Lett. 2018. PMID: 29489381 Free PMC article.
High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing.
Sago CD, Lokugamage MP, Paunovska K, Vanover DA, Monaco CM, Shah NN, Gamboa Castro M, Anderson SE, Rudoltz TG, Lando GN, Munnilal Tiwari P, Kirschman JL, Willett N, Jang YC, Santangelo PJ, Bryksin AV, Dahlman JE. Sago CD, et al. Among authors: santangelo pj. Proc Natl Acad Sci U S A. 2018 Oct 16;115(42):E9944-E9952. doi: 10.1073/pnas.1811276115. Epub 2018 Oct 1. Proc Natl Acad Sci U S A. 2018. PMID: 30275336 Free PMC article.
Modification of primary amines to higher order amines reduces in vivo hematological and immunotoxicity of cationic nanocarriers through TLR4 and complement pathways.
Toy R, Pradhan P, Ramesh V, Di Paolo NC, Lash B, Liu J, Blanchard EL, Pinelli CJ, Santangelo PJ, Shayakhmetov DM, Roy K. Toy R, et al. Among authors: santangelo pj. Biomaterials. 2019 Dec;225:119512. doi: 10.1016/j.biomaterials.2019.119512. Epub 2019 Sep 21. Biomaterials. 2019. PMID: 31585233
Aerosol Delivery of Synthetic mRNA to Vaginal Mucosa Leads to Durable Expression of Broadly Neutralizing Antibodies against HIV.
Lindsay KE, Vanover D, Thoresen M, King H, Xiao P, Badial P, Araínga M, Park SB, Tiwari PM, Peck HE, Blanchard EL, Feugang JM, Olivier AK, Zurla C, Villinger F, Woolums AR, Santangelo PJ. Lindsay KE, et al. Among authors: santangelo pj. Mol Ther. 2020 Mar 4;28(3):805-819. doi: 10.1016/j.ymthe.2020.01.002. Epub 2020 Jan 10. Mol Ther. 2020. PMID: 31995741 Free PMC article.
93 results