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A Systematic Survey of Reversibly Covalent Dipeptidyl Inhibitors of the SARS-CoV-2 Main Protease.
Geng ZZ, Atla S, Shaabani N, Vulupala VR, Yang KS, Alugubelli YR, Khatua K, Chen PC, Xiao J, Blankenship LR, Ma XR, Vatansever EC, Cho CC, Ma Y, Allen R, Ji H, Xu S, Liu WR. Geng ZZ, et al. Among authors: ji h. bioRxiv [Preprint]. 2023 Jan 18:2023.01.17.524469. doi: 10.1101/2023.01.17.524469. bioRxiv. 2023. Update in: J Med Chem. 2023 Aug 24;66(16):11040-11055. doi: 10.1021/acs.jmedchem.3c00221 PMID: 36711580 Free PMC article. Updated. Preprint.
The P3 O - Tert -Butyl-Threonine is Key to High Cellular and Antiviral Potency for Aldehyde-Based SARS-CoV-2 Main Protease Inhibitors.
Ma Y, Yang KS, Geng ZZ, Alugubelli YR, Shaabani N, Vatansever EC, Ma XR, Cho CC, Khatua K, Blankenship L, Yu G, Sankaran B, Li P, Allen R, Ji H, Xu S, Liu WR. Ma Y, et al. Among authors: ji h. bioRxiv [Preprint]. 2021 Dec 21:2021.12.18.473326. doi: 10.1101/2021.12.18.473326. bioRxiv. 2021. PMID: 34981047 Free PMC article. Preprint.
The N -Terminal Carbamate is Key to High Cellular and Antiviral Potency for Boceprevir-Based SARS-CoV-2 Main Protease Inhibitors.
Alugubelli YR, Geng ZZ, Yang KS, Shaabani N, Khatua K, Ma XR, Vatansever EC, Cho CC, Ma Y, Blankenship L, Yu G, Sankaran B, Li P, Allen R, Ji H, Xu S, Liu WR. Alugubelli YR, et al. Among authors: ji h. bioRxiv [Preprint]. 2021 Dec 21:2021.12.18.473330. doi: 10.1101/2021.12.18.473330. bioRxiv. 2021. PMID: 34981058 Free PMC article. Preprint.
Olgotrelvir, a dual inhibitor of SARS-CoV-2 Mpro and cathepsin L, as a standalone antiviral oral intervention candidate for COVID-19.
Mao L, Shaabani N, Zhang X, Jin C, Xu W, Argent C, Kushnareva Y, Powers C, Stegman K, Liu J, Xie H, Xu C, Bao Y, Xu L, Zhang Y, Yang H, Qian S, Hu Y, Shao J, Zhang C, Li T, Li Y, Liu N, Lin Z, Wang S, Wang C, Shen W, Lin Y, Shu D, Zhu Z, Kotoi O, Kerwin L, Han Q, Chumakova L, Teijaro J, Royal M, Brunswick M, Allen R, Ji H, Lu H, Xu X. Mao L, et al. Among authors: ji h. Med. 2024 Feb 9;5(2):169-171. doi: 10.1016/j.medj.2024.01.013. Med. 2024. PMID: 38340710 Free article. No abstract available.
UDA-seq: universal droplet microfluidics-based combinatorial indexing for massive-scale multimodal single-cell sequencing.
Li Y, Huang Z, Xu L, Fan Y, Ping J, Li G, Chen Y, Yu C, Wang Q, Song T, Lin T, Liu M, Xu Y, Ai N, Meng X, Qiao Q, Ji H, Qin Z, Jin S, Jiang N, Wang M, Shu S, Zhang F, Zhang W, Liu GH, Chen L, Jiang L. Li Y, et al. Among authors: ji h. Nat Methods. 2025 Jan 20. doi: 10.1038/s41592-024-02586-y. Online ahead of print. Nat Methods. 2025. PMID: 39833568
6,765 results