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DNA methylation analysis is used to identify novel genetic loci associated with circulating fibrinogen levels in blood.
Hahn J, Bressler J, Domingo-Relloso A, Chen MH, McCartney DL, Teumer A, van Dongen J, Kleber ME, Aïssi D, Swenson BR, Yao J, Zhao W, Huang J, Xia Y, Brown MR, Costeira R, de Geus EJC, Delgado GE, Dobson DA, Elliott P, Grabe HJ, Guo X, Harris SE, Huffman JE, Kardia SLR, Liu Y, Lorkowski S, Marioni RE, Nauck M, Ratliff SM, Sabater-Lleal M, Spector TD, Suchon P, Taylor KD, Thibord F, Trégouët DA, Wiggins KL, Willemsen G, Bell JT, Boomsma DI, Cole SA, Cox SR, Dehghan A, Greinacher A, Haack K, März W, Morange PE, Rotter JI, Sotoodehnia N, Tellez-Plaza M, Navas-Acien A, Smith JA, Johnson AD, Fornage M, Smith NL, Wolberg AS, Morrison AC, de Vries PS. Hahn J, et al. Among authors: van dongen j. J Thromb Haemost. 2023 May;21(5):1135-1147. doi: 10.1016/j.jtha.2023.01.015. Epub 2023 Jan 28. J Thromb Haemost. 2023. PMID: 36716967 Free PMC article.
The continuing value of twin studies in the omics era.
van Dongen J, Slagboom PE, Draisma HH, Martin NG, Boomsma DI. van Dongen J, et al. Nat Rev Genet. 2012 Sep;13(9):640-53. doi: 10.1038/nrg3243. Epub 2012 Jul 31. Nat Rev Genet. 2012. PMID: 22847273 Review.
Sex differences in genetic architecture of complex phenotypes?
Vink JM, Bartels M, van Beijsterveldt TC, van Dongen J, van Beek JH, Distel MA, de Moor MH, Smit DJ, Minica CC, Ligthart L, Geels LM, Abdellaoui A, Middeldorp CM, Hottenga JJ, Willemsen G, de Geus EJ, Boomsma DI. Vink JM, et al. Among authors: van beek jh, van beijsterveldt tc, van dongen j. PLoS One. 2012;7(12):e47371. doi: 10.1371/journal.pone.0047371. Epub 2012 Dec 18. PLoS One. 2012. PMID: 23272036 Free PMC article.
The Adult Netherlands Twin Register: twenty-five years of survey and biological data collection.
Willemsen G, Vink JM, Abdellaoui A, den Braber A, van Beek JH, Draisma HH, van Dongen J, van 't Ent D, Geels LM, van Lien R, Ligthart L, Kattenberg M, Mbarek H, de Moor MH, Neijts M, Pool R, Stroo N, Kluft C, Suchiman HE, Slagboom PE, de Geus EJ, Boomsma DI. Willemsen G, et al. Among authors: van beek jh, van lien r, van t ent d, van dongen j. Twin Res Hum Genet. 2013 Feb;16(1):271-81. doi: 10.1017/thg.2012.140. Epub 2013 Jan 8. Twin Res Hum Genet. 2013. PMID: 23298648 Free PMC article.
Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease.
Sabater-Lleal M, Huang J, Chasman D, Naitza S, Dehghan A, Johnson AD, Teumer A, Reiner AP, Folkersen L, Basu S, Rudnicka AR, Trompet S, Mälarstig A, Baumert J, Bis JC, Guo X, Hottenga JJ, Shin SY, Lopez LM, Lahti J, Tanaka T, Yanek LR, Oudot-Mellakh T, Wilson JF, Navarro P, Huffman JE, Zemunik T, Redline S, Mehra R, Pulanic D, Rudan I, Wright AF, Kolcic I, Polasek O, Wild SH, Campbell H, Curb JD, Wallace R, Liu S, Eaton CB, Becker DM, Becker LC, Bandinelli S, Räikkönen K, Widen E, Palotie A, Fornage M, Green D, Gross M, Davies G, Harris SE, Liewald DC, Starr JM, Williams FM, Grant PJ, Spector TD, Strawbridge RJ, Silveira A, Sennblad B, Rivadeneira F, Uitterlinden AG, Franco OH, Hofman A, van Dongen J, Willemsen G, Boomsma DI, Yao J, Swords Jenny N, Haritunians T, McKnight B, Lumley T, Taylor KD, Rotter JI, Psaty BM, Peters A, Gieger C, Illig T, Grotevendt A, Homuth G, Völzke H, Kocher T, Goel A, Franzosi MG, Seedorf U, Clarke R, Steri M, Tarasov KV, Sanna S, Schlessinger D, Stott DJ, Sattar N, Buckley BM, Rumley A, Lowe GD, McArdle WL, Chen MH, Tofler GH, Song J, Boerwinkle E, Folsom AR, Rose LM, Franco-Cereceda A, Teichert M, Ikram MA, Mosley TH, Bevan S, Dichgans M, Rothw… See abstract for full author list ➔ Sabater-Lleal M, et al. Among authors: van dongen j. Circulation. 2013 Sep 17;128(12):1310-24. doi: 10.1161/CIRCULATIONAHA.113.002251. Epub 2013 Aug 22. Circulation. 2013. PMID: 23969696 Free PMC article.
1,298 results