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A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.
Simon M, Yang J, Gigas J, Earley EJ, Hillpot E, Zhang L, Zagorulya M, Tombline G, Gilbert M, Yuen SL, Pope A, Van Meter M, Emmrich S, Firsanov D, Athreya A, Biashad SA, Han J, Ryu S, Tare A, Zhu Y, Hudgins A, Atzmon G, Barzilai N, Wolfe A, Moody K, Garcia BA, Robbins PD, Vijg J, Seluanov A, Suh Y, Gorbunova V. Simon M, et al. Among authors: tombline g. EMBO J. 2023 Feb 1;42(3):e113326. doi: 10.15252/embj.2022113326. EMBO J. 2023. PMID: 36722290 Free PMC article.
Hyaluronidase inhibitor delphinidin inhibits cancer metastasis.
McGuire J, Taguchi T, Tombline G, Paige V, Janelsins M, Gilmore N, Seluanov A, Gorbunova V. McGuire J, et al. Among authors: tombline g. Sci Rep. 2024 Jun 28;14(1):14958. doi: 10.1038/s41598-024-64924-6. Sci Rep. 2024. PMID: 38942920 Free PMC article.
DNA repair and anti-cancer mechanisms in the long-lived bowhead whale.
Firsanov D, Zacher M, Tian X, Sformo TL, Zhao Y, Tombline G, Lu JY, Zheng Z, Perelli L, Gurreri E, Zhang L, Guo J, Korotkov A, Volobaev V, Biashad SA, Zhang Z, Heid J, Maslov A, Sun S, Wu Z, Gigas J, Hillpot E, Martinez J, Lee M, Williams A, Gilman A, Hamilton N, Haseljic E, Patel A, Straight M, Miller N, Ablaeva J, Tam LM, Couderc C, Hoopman M, Moritz R, Fujii S, Hayman DJ, Liu H, Cai Y, Leung AKL, Simons MJP, Zhang Z, Nelson CB, Abegglen LM, Schiffman JD, Gladyshev VN, Modesti M, Genovese G, Vijg J, Seluanov A, Gorbunova V. Firsanov D, et al. Among authors: tombline g. bioRxiv [Preprint]. 2024 Nov 5:2023.05.07.539748. doi: 10.1101/2023.05.07.539748. bioRxiv. 2024. PMID: 39574710 Free PMC article. Preprint.
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A.
Simon M, Yang J, Gigas J, Earley EJ, Hillpot E, Zhang L, Zagorulya M, Tombline G, Gilbert M, Yuen SL, Pope A, Van Meter M, Emmrich S, Firsanov D, Athreya A, Biashad SA, Han J, Ryu S, Tare A, Zhu Y, Hudgins A, Atzmon G, Barzilai N, Wolfe A, Moody K, Garcia BA, Thomas DD, Robbins PD, Vijg J, Seluanov A, Suh Y, Gorbunova V. Simon M, et al. Among authors: tombline g. EMBO J. 2022 Nov 2;41(21):e110393. doi: 10.15252/embj.2021110393. Epub 2022 Oct 10. EMBO J. 2022. PMID: 36215696 Free PMC article.
Proteomics of Long-Lived Mammals.
Tombline G, Gigas J, Macoretta N, Zacher M, Emmrich S, Zhao Y, Seluanov A, Gorbunova V. Tombline G, et al. Proteomics. 2020 Mar;20(5-6):e1800416. doi: 10.1002/pmic.201800416. Epub 2020 Jan 9. Proteomics. 2020. PMID: 31737995 Free PMC article. Review.
45 results