Hanessian S - Search Results

1

Synthesis of Azabicyclic Isosteres of Piperazine 2S-Carboxylic Acid.

Vaillancourt M, Mishra A, Duchamp E, Hanessian S. Vaillancourt M, et al. Among authors: hanessian s. J Org Chem. 2024 Oct 18;89(20):15170-15186. doi: 10.1021/acs.joc.4c01944. Epub 2024 Oct 2. J Org Chem. 2024. PMID: 39358033

2

Towards combining backbone and sugar constraint in 3'-3' bis-phosphonate tethered 2'-4' bridged LNA oligonucleotide trimers.

Duchamp E, Vasquez G, Firoozi N, Freestone GC, Oestergaard M, Seth PP, Hanessian S. Duchamp E, et al. Among authors: hanessian s. RSC Adv. 2024 Jul 26;14(33):23583-23591. doi: 10.1039/d4ra04277h. eCollection 2024 Jul 26. RSC Adv. 2024. PMID: 39070250 Free PMC article.

3

Revisiting the dipeptidyl carboxypeptidase inhibitor captopril as a source of pan anti-trypanosomatid agents.

Garsi JB, Hocine S, Hensienne R, Moitessier M, Denton H, Major LL, Smith TK, Hanessian S. Garsi JB, et al. Among authors: hanessian s. Bioorg Med Chem Lett. 2024 Sep 15;110:129883. doi: 10.1016/j.bmcl.2024.129883. Epub 2024 Jul 14. Bioorg Med Chem Lett. 2024. PMID: 39013490

4

My 50-Plus Years of Academic Research Collaborations with Industry. A Retrospective.

Hanessian S. Hanessian S. J Org Chem. 2024 Jul 5;89(13):9147-9186. doi: 10.1021/acs.joc.4c00652. Epub 2024 Jun 12. J Org Chem. 2024. PMID: 38865159 Review.

5

Pseudodiproline (Pro-Cyp) Oligomers Fold into Helical Polyproline Type secondary structures.

Garsi JB, Aguiar PM, Berger G, Maris T, Hanessian S. Garsi JB, et al. Among authors: hanessian s. J Org Chem. 2024 Apr 5;89(7):4283-4293. doi: 10.1021/acs.joc.3c02840. Epub 2024 Mar 15. J Org Chem. 2024. PMID: 38489026 Review.

6

Synthesis of Aza-Bridged Perhydroazulene Chimeras of Tropanes and Hederacine A.

Hocine S, Duchamp E, Mishra A, Fourquez JM, Hanessian S. Hocine S, et al. Among authors: hanessian s. J Org Chem. 2023 Apr 7;88(7):4675-4686. doi: 10.1021/acs.joc.3c00169. Epub 2023 Mar 20. J Org Chem. 2023. PMID: 36940388

7

Systematic Investigation of Tether Length and Phosphorus Configuration in Backbone Constrained Macrocyclic Nucleic Acids to Modulate Binding Kinetics for RNA.

Rajasekaran T, Freestone GC, Galindo-Murillo R, Lugato B, Gaus H, Migawa MT, Swayze EE, Cheatham TE 3rd, Seth PP, Hanessian S. Rajasekaran T, et al. Among authors: hanessian s. J Org Chem. 2023 Mar 17;88(6):3599-3614. doi: 10.1021/acs.joc.2c02796. Epub 2023 Mar 1. J Org Chem. 2023. PMID: 36857642

8

Simultaneous inhibition of endocytic recycling and lysosomal fusion sensitizes cells and tissues to oligonucleotide therapeutics.

Finicle BT, Eckenstein KH, Revenko AS, Anderson BA, Wan WB, McCracken AN, Gil D, Fruman DA, Hanessian S, Seth PP, Edinger AL. Finicle BT, et al. Among authors: hanessian s. Nucleic Acids Res. 2023 Feb 28;51(4):1583-1599. doi: 10.1093/nar/gkad023. Nucleic Acids Res. 2023. PMID: 36727438 Free PMC article.

9

Polygonapholine: A Total Synthesis Questions the Identity for the Purported Structure of the Natural Product.

Duchamp E, Devin R, Aguiar PM, Gaucherand A, Hanessian S. Duchamp E, et al. Among authors: hanessian s. J Org Chem. 2022 Nov 18;87(22):15713-15718. doi: 10.1021/acs.joc.2c02339. Epub 2022 Nov 9. J Org Chem. 2022. PMID: 36349937

10

Targeting non-alcoholic fatty liver disease: Design, X-ray co-crystal structure and synthesis of 'first-in-kind' inhibitors of serine/threonine kinase25.

Kiyeleko S, Hocine S, Mautino G, Kuenemann M, Nawrotek A, Miallau L, Vuillard LM, Mirguet O, Kotschy A, Hanessian S. Kiyeleko S, et al. Among authors: hanessian s. Bioorg Med Chem Lett. 2022 Nov 1;75:128950. doi: 10.1016/j.bmcl.2022.128950. Epub 2022 Aug 24. Bioorg Med Chem Lett. 2022. PMID: 36030002

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