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Oxidative phosphorylation selectively orchestrates tissue macrophage homeostasis.
Wculek SK, Heras-Murillo I, Mastrangelo A, Mañanes D, Galán M, Miguel V, Curtabbi A, Barbas C, Chandel NS, Enríquez JA, Lamas S, Sancho D. Wculek SK, et al. Among authors: chandel ns. Immunity. 2023 Mar 14;56(3):516-530.e9. doi: 10.1016/j.immuni.2023.01.011. Epub 2023 Feb 3. Immunity. 2023. PMID: 36738738 Free article.
Post-ischemic inactivation of HIF prolyl hydroxylases in endothelium promotes maladaptive kidney repair by inducing glycolysis.
Tiwari R, Sharma R, Rajendran G, Borkowski GS, An SY, Schonfeld M, O'Sullivan J, Schipma MJ, Zhou Y, Courbon G, David V, Quaggin SE, Thorp E, Chandel NS, Kapitsinou PP. Tiwari R, et al. Among authors: chandel ns. bioRxiv [Preprint]. 2023 Oct 3:2023.10.03.560700. doi: 10.1101/2023.10.03.560700. bioRxiv. 2023. Update in: J Clin Invest. 2024 Nov 26:e176207. doi: 10.1172/JCI176207 PMID: 37873349 Free PMC article. Updated. Preprint.
Octopamine metabolically reprograms astrocytes to confer neuroprotection against α-synuclein.
Shum A, Zaichick S, McElroy GS, D'Alessandro K, Alasady MJ, Novakovic M, Peng W, Grebenik EA, Chung D, Flanagan ME, Smith R, Morales A, Stumpf L, McGrath K, Krainc D, Mendillo ML, Prakriya M, Chandel NS, Caraveo G. Shum A, et al. Among authors: chandel ns. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e2217396120. doi: 10.1073/pnas.2217396120. Epub 2023 Apr 17. Proc Natl Acad Sci U S A. 2023. PMID: 37068235 Free PMC article.
A Drosophila model of mitochondrial disease phenotypic heterogeneity.
Granat L, Knorr DY, Ranson DC, Chakrabarty RP, Chandel NS, Bateman JM. Granat L, et al. Among authors: chandel ns. Biol Open. 2024 Feb 15;13(2):bio060278. doi: 10.1242/bio.060278. Epub 2024 Feb 28. Biol Open. 2024. PMID: 38304969 Free PMC article.
Metformin targets mitochondrial complex I to lower blood glucose levels.
Reczek CR, Chakrabarty RP, D'Alessandro KB, Sebo ZL, Grant RA, Gao P, Budinger GR, Chandel NS. Reczek CR, et al. Among authors: chandel ns. Sci Adv. 2024 Dec 20;10(51):eads5466. doi: 10.1126/sciadv.ads5466. Epub 2024 Dec 18. Sci Adv. 2024. PMID: 39693440 Free PMC article.
IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma.
Karakousi T, Cristaldi V, Lopes de Oliveira ML, Medeiros Geraldo LH, González-Robles TJ, da Silva G, Breazeale AP, Encarnacion-Rosado J, Pozniak J, Kimmelman AC, Ruggles KV, Chris Marine J, Chandel NS, Lund AW. Karakousi T, et al. Among authors: chandel ns. bioRxiv [Preprint]. 2024 Dec 5:2024.12.02.626426. doi: 10.1101/2024.12.02.626426. bioRxiv. 2024. PMID: 39677662 Free PMC article. Preprint.
312 results