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A whole-genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain tumors.
Taubenschmid-Stowers J, Orthofer M, Laemmerer A, Krauditsch C, Rózsová M, Studer C, Lötsch D, Gojo J, Gabler L, Dyczynski M, Efferth T, Hagelkruys A, Widhalm G, Peyrl A, Spiegl-Kreinecker S, Hoepfner D, Bian S, Berger W, Knoblich JA, Elling U, Horn M, Penninger JM. Taubenschmid-Stowers J, et al. Among authors: efferth t. EMBO Mol Med. 2023 Mar 8;15(3):e16959. doi: 10.15252/emmm.202216959. Epub 2023 Feb 6. EMBO Mol Med. 2023. PMID: 36740985 Free PMC article.
A drug repurposing approach for individualized cancer therapy based on transcriptome sequencing and virtual drug screening.
Kadioglu O, Bahramimehr F, Dawood M, Mahmoud N, Elbadawi M, Lu X, Bülbül Y, Schulz JA, Krämer L, Urschel MK, Künzli Z, Abdulrahman L, Aboumaachar F, Kadalo L, Nguyen LV, Shaidaei S, Thaher N, Walter K, Besler KC, Spuller A, Munder M, Greten HJ, Efferth T. Kadioglu O, et al. Among authors: efferth t. Comput Biol Med. 2023 May;157:106781. doi: 10.1016/j.compbiomed.2023.106781. Epub 2023 Mar 11. Comput Biol Med. 2023. PMID: 36931205
Natural products targeting tumour angiogenesis.
Lu X, Friedrich LJ, Efferth T. Lu X, et al. Among authors: efferth t. Br J Pharmacol. 2023 Sep 7. doi: 10.1111/bph.16232. Online ahead of print. Br J Pharmacol. 2023. PMID: 37680009 Free article. Review.
TCTP regulates genotoxic stress and tumorigenicity via intercellular vesicular signaling.
Amson R, Senff-Ribeiro A, Karafin T, Lespagnol A, Honoré J, Baylot V, Banroques J, Tanner NK, Chamond N, Dimitrov JD, Hoebeke J, Droin NM, Job B, Piard J, Bommer UA, Choi KW, Abdelfatah S, Efferth T, Telerman SB, Geyer FC, Reis-Filho J, Telerman A. Amson R, et al. Among authors: efferth t. EMBO Rep. 2024 Apr;25(4):1962-1986. doi: 10.1038/s44319-024-00108-7. Epub 2024 Mar 28. EMBO Rep. 2024. PMID: 38548973 Free PMC article.
868 results