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Targeting CD38 with monoclonal antibodies disrupts key survival pathways in paediatric Burkitt's lymphoma malignant B cells.
Kläsener K, Herrmann N, Håversen L, Sundell T, Sundqvist M, Lundqvist C, Manna PT, Jonsson CA, Visentini M, Ljung Sass D, McGrath S, Grimstad K, Aranburu A, Mellgren K, Fogelstrand L, Forsman H, Ekwall O, Borén J, Gjertsson I, Reth M, Mårtensson IL, Camponeschi A. Kläsener K, et al. Among authors: boren j. Clin Transl Immunology. 2024 Oct 3;13(10):e70011. doi: 10.1002/cti2.70011. eCollection 2024. Clin Transl Immunology. 2024. PMID: 39364393 Free PMC article.
Design and synthesis of novel JNK inhibitors targeting liver pyruvate kinase for the treatment of non-alcoholic fatty liver disease and hepatocellular carcinoma.
Iqbal S, Sebhaoui J, Ashraf S, Ozcan M, Kim W, Belmen B, Yeşilyurt G, Hanashalshahaby E, Zhang C, Uhlen M, Boren J, Turkez H, Mardinoglu A. Iqbal S, et al. Among authors: boren j. Bioorg Chem. 2024 Jun;147:107425. doi: 10.1016/j.bioorg.2024.107425. Epub 2024 May 3. Bioorg Chem. 2024. PMID: 38714117
Cardiomyocytes, sphingolipids and cardio myotoxicity.
Levin MC, Andersson L, Borén J. Levin MC, et al. Among authors: boren j. Curr Opin Lipidol. 2023 Aug 1;34(4):180-188. doi: 10.1097/MOL.0000000000000829. Curr Opin Lipidol. 2023. PMID: 37431304 Review.
Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases.
Turkez H, Altay O, Yildirim S, Li X, Yang H, Bayram C, Bolat I, Oner S, Tozlu OO, Arslan ME, Arif M, Yulug B, Hanoglu L, Cankaya S, Lam S, Velioglu HA, Coskun E, Idil E, Nogaylar R, Ozsimsek A, Hacimuftuoglu A, Shoaie S, Zhang C, Nielsen J, Borén J, Uhlén M, Mardinoglu A. Turkez H, et al. Among authors: boren j. Life Sci. 2023 Feb 1;314:121325. doi: 10.1016/j.lfs.2022.121325. Epub 2022 Dec 26. Life Sci. 2023. Retraction in: Life Sci. 2024 Jul 15;349:122712. doi: 10.1016/j.lfs.2024.122712 PMID: 36581096 Free article. Retracted.
491 results