Hao-Shen H - Search Results

1

Iron is a modifier of the phenotypes of JAK2-mutant myeloproliferative neoplasms.

Stetka J, Usart M, Kubovcakova L, Rai S, Rao TN, Sutter J, Hao-Shen H, Dirnhofer S, Geier F, Bader MS, Passweg JR, Manolova V, Dürrenberger F, Ahmed N, Schroeder T, Ganz T, Nemeth E, Silvestri L, Nai A, Camaschella C, Skoda RC. Stetka J, et al. Among authors: hao shen h. Blood. 2023 Apr 27;141(17):2127-2140. doi: 10.1182/blood.2022017976. Blood. 2023. PMID: 36758212 Free article.

2

Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo.

Tiedt R, Schomber T, Hao-Shen H, Skoda RC. Tiedt R, et al. Blood. 2007 Feb 15;109(4):1503-6. doi: 10.1182/blood-2006-04-020362. Epub 2006 Oct 10. Blood. 2007. PMID: 17032923 Free article.

3

Normal erythropoiesis but severe polyposis and bleeding anemia in Smad4-deficient mice.

Pan D, Schomber T, Kalberer CP, Terracciano LM, Hafen K, Krenger W, Hao-Shen H, Deng C, Skoda RC. Pan D, et al. Blood. 2007 Oct 15;110(8):3049-55. doi: 10.1182/blood-2007-02-074393. Epub 2007 Jul 16. Blood. 2007. PMID: 17638848 Free article.

4

Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice.

Tiedt R, Hao-Shen H, Sobas MA, Looser R, Dirnhofer S, Schwaller J, Skoda RC. Tiedt R, et al. Blood. 2008 Apr 15;111(8):3931-40. doi: 10.1182/blood-2007-08-107748. Epub 2007 Dec 26. Blood. 2008. PMID: 18160670 Free article.

5

The allele burden of JAK2 mutations remains stable over several years in patients with myeloproliferative disorders.

Theocharides A, Passweg JR, Medinger M, Looser R, Li S, Hao-Shen H, Buser AS, Gratwohl A, Tichelli A, Skoda RC. Theocharides A, et al. Haematologica. 2008 Dec;93(12):1890-3. doi: 10.3324/haematol.13074. Epub 2008 Sep 11. Haematologica. 2008. PMID: 18790796 Free article.

6

Pronounced thrombocytosis in transgenic mice expressing reduced levels of Mpl in platelets and terminally differentiated megakaryocytes.

Tiedt R, Coers J, Ziegler S, Wiestner A, Hao-Shen H, Bornmann C, Schenkel J, Karakhanova S, de Sauvage FJ, Jackson CW, Skoda RC. Tiedt R, et al. Blood. 2009 Feb 19;113(8):1768-77. doi: 10.1182/blood-2008-03-146084. Epub 2008 Oct 9. Blood. 2009. PMID: 18845793 Free article.

7

Clonal analysis of deletions on chromosome 20q and JAK2-V617F in MPD suggests that del20q acts independently and is not one of the predisposing mutations for JAK2-V617F.

Schaub FX, Jäger R, Looser R, Hao-Shen H, Hermouet S, Girodon F, Tichelli A, Gisslinger H, Kralovics R, Skoda RC. Schaub FX, et al. Blood. 2009 Feb 26;113(9):2022-7. doi: 10.1182/blood-2008-07-167056. Epub 2008 Dec 1. Blood. 2009. PMID: 19047681 Free article.

8

Clonal analysis of TET2 and JAK2 mutations suggests that TET2 can be a late event in the progression of myeloproliferative neoplasms.

Schaub FX, Looser R, Li S, Hao-Shen H, Lehmann T, Tichelli A, Skoda RC. Schaub FX, et al. Blood. 2010 Mar 11;115(10):2003-7. doi: 10.1182/blood-2009-09-245381. Epub 2010 Jan 8. Blood. 2010. PMID: 20061559 Free article.

9

Transition to homozygosity does not appear to provide a clonal advantage to hematopoietic progenitors carrying mutations in TET2.

Schaub FX, Lehmann T, Looser R, Hao-Shen H, Tichelli A, Skoda RC. Schaub FX, et al. Blood. 2011 Feb 10;117(6):2075-6. doi: 10.1182/blood-2010-11-316471. Blood. 2011. PMID: 21310937 Free article. No abstract available.

10

Differential effects of hydroxyurea and INC424 on mutant allele burden and myeloproliferative phenotype in a JAK2-V617F polycythemia vera mouse model.

Kubovcakova L, Lundberg P, Grisouard J, Hao-Shen H, Romanet V, Andraos R, Murakami M, Dirnhofer S, Wagner KU, Radimerski T, Skoda RC. Kubovcakova L, et al. Blood. 2013 Feb 14;121(7):1188-99. doi: 10.1182/blood-2012-03-415646. Epub 2012 Dec 20. Blood. 2013. PMID: 23264594 Free article.

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