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An optimized bioluminescent substrate for non-invasive imaging in the brain.
Su Y, Walker JR, Hall MP, Klein MA, Wu X, Encell LP, Casey KM, Liu LX, Hong G, Lin MZ, Kirkland TA. Su Y, et al. Among authors: casey km. Nat Chem Biol. 2023 Jun;19(6):731-739. doi: 10.1038/s41589-023-01265-x. Epub 2023 Feb 9. Nat Chem Biol. 2023. PMID: 36759751 Free PMC article.
Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals.
Su Y, Walker JR, Park Y, Smith TP, Liu LX, Hall MP, Labanieh L, Hurst R, Wang DC, Encell LP, Kim N, Zhang F, Kay MA, Casey KM, Majzner RG, Cochran JR, Mackall CL, Kirkland TA, Lin MZ. Su Y, et al. Among authors: casey km. Nat Methods. 2020 Aug;17(8):852-860. doi: 10.1038/s41592-020-0889-6. Epub 2020 Jul 13. Nat Methods. 2020. PMID: 32661427 Free PMC article.
SETD3 is an actin histidine methyltransferase that prevents primary dystocia.
Wilkinson AW, Diep J, Dai S, Liu S, Ooi YS, Song D, Li TM, Horton JR, Zhang X, Liu C, Trivedi DV, Ruppel KM, Vilches-Moure JG, Casey KM, Mak J, Cowan T, Elias JE, Nagamine CM, Spudich JA, Cheng X, Carette JE, Gozani O. Wilkinson AW, et al. Among authors: casey km. Nature. 2019 Jan;565(7739):372-376. doi: 10.1038/s41586-018-0821-8. Epub 2018 Dec 10. Nature. 2019. PMID: 30626964 Free PMC article.
AND-gate contrast agents for enhanced fluorescence-guided surgery.
Widen JC, Tholen M, Yim JJ, Antaris A, Casey KM, Rogalla S, Klaassen A, Sorger J, Bogyo M. Widen JC, et al. Among authors: casey km. Nat Biomed Eng. 2021 Mar;5(3):264-277. doi: 10.1038/s41551-020-00616-6. Epub 2020 Sep 28. Nat Biomed Eng. 2021. PMID: 32989286 Free PMC article.
Neuroelectrophysiology-compatible electrolytic lesioning.
Bray IE, Clarke SE, Casey KM, Nuyujukian P; Brain Interfacing Laboratory. Bray IE, et al. Among authors: casey km. Elife. 2024 Sep 11;12:RP84385. doi: 10.7554/eLife.84385. Elife. 2024. PMID: 39259198 Free PMC article.
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.
Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR. Pedram K, et al. Among authors: casey km. Nat Biotechnol. 2024 Apr;42(4):597-607. doi: 10.1038/s41587-023-01840-6. Epub 2023 Aug 3. Nat Biotechnol. 2024. PMID: 37537499 Free PMC article.
Mitochondrial copper depletion suppresses triple-negative breast cancer in mice.
Cui L, Gouw AM, LaGory EL, Guo S, Attarwala N, Tang Y, Qi J, Chen YS, Gao Z, Casey KM, Bazhin AA, Chen M, Hu L, Xie J, Fang M, Zhang C, Zhu Q, Wang Z, Giaccia AJ, Gambhir SS, Zhu W, Felsher DW, Pegram MD, Goun EA, Le A, Rao J. Cui L, et al. Among authors: casey km. Nat Biotechnol. 2021 Mar;39(3):357-367. doi: 10.1038/s41587-020-0707-9. Epub 2020 Oct 19. Nat Biotechnol. 2021. PMID: 33077961 Free PMC article.
Western diet regulates immune status and the response to LPS-driven sepsis independent of diet-associated microbiome.
Napier BA, Andres-Terre M, Massis LM, Hryckowian AJ, Higginbottom SK, Cumnock K, Casey KM, Haileselassie B, Lugo KA, Schneider DS, Sonnenburg JL, Monack DM. Napier BA, et al. Among authors: casey km. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3688-3694. doi: 10.1073/pnas.1814273116. Epub 2019 Feb 11. Proc Natl Acad Sci U S A. 2019. PMID: 30808756 Free PMC article.
81 results