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Tolerogenic dendritic cells generated with dexamethasone and vitamin D3 regulate rheumatoid arthritis CD4+ T cells partly via transforming growth factor-β1.
Anderson AE, Swan DJ, Wong OY, Buck M, Eltherington O, Harry RA, Patterson AM, Pratt AG, Reynolds G, Doran JP, Kirby JA, Isaacs JD, Hilkens CM. Anderson AE, et al. Among authors: pratt ag. Clin Exp Immunol. 2017 Jan;187(1):113-123. doi: 10.1111/cei.12870. Epub 2016 Nov 2. Clin Exp Immunol. 2017. PMID: 27667787 Free PMC article.
Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23.
McGovern A, Schoenfelder S, Martin P, Massey J, Duffus K, Plant D, Yarwood A, Pratt AG, Anderson AE, Isaacs JD, Diboll J, Thalayasingam N, Ospelt C, Barton A, Worthington J, Fraser P, Eyre S, Orozco G. McGovern A, et al. Among authors: pratt ag. Genome Biol. 2016 Nov 1;17(1):212. doi: 10.1186/s13059-016-1078-x. Genome Biol. 2016. PMID: 27799070 Free PMC article.
The interferon gene signature is increased in patients with early treatment-naive rheumatoid arthritis and predicts a poorer response to initial therapy.
Cooles FAH, Anderson AE, Lendrem DW, Norris J, Pratt AG, Hilkens CMU, Isaacs JD. Cooles FAH, et al. Among authors: pratt ag. J Allergy Clin Immunol. 2018 Jan;141(1):445-448.e4. doi: 10.1016/j.jaci.2017.08.026. Epub 2017 Oct 5. J Allergy Clin Immunol. 2018. PMID: 28987811 Free PMC article. No abstract available.
CD4+ and B Lymphocyte Expression Quantitative Traits at Rheumatoid Arthritis Risk Loci in Patients With Untreated Early Arthritis: Implications for Causal Gene Identification.
Thalayasingam N, Nair N, Skelton AJ, Massey J, Anderson AE, Clark AD, Diboll J, Lendrem DW, Reynard LN, Cordell HJ, Eyre S, Isaacs JD, Barton A, Pratt AG. Thalayasingam N, et al. Among authors: pratt ag. Arthritis Rheumatol. 2018 Mar;70(3):361-370. doi: 10.1002/art.40393. Epub 2018 Jan 30. Arthritis Rheumatol. 2018. PMID: 29193869 Free PMC article.
What are the dominant cytokines in early rheumatoid arthritis?
Ridgley LA, Anderson AE, Pratt AG. Ridgley LA, et al. Among authors: pratt ag. Curr Opin Rheumatol. 2018 Mar;30(2):207-214. doi: 10.1097/BOR.0000000000000470. Curr Opin Rheumatol. 2018. PMID: 29206659 Free PMC article. Review.
103 results