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Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos.
McGarvey AC, Kopp W, Vučićević D, Mattonet K, Kempfer R, Hirsekorn A, Bilić I, Gil M, Trinks A, Merks AM, Panáková D, Pombo A, Akalin A, Junker JP, Stainier DYR, Garfield D, Ohler U, Lacadie SA. McGarvey AC, et al. Among authors: ohler u. Cell Genom. 2022 Jan 13;2(1):100083. doi: 10.1016/j.xgen.2021.100083. eCollection 2022 Jan 12. Cell Genom. 2022. PMID: 36777038 Free PMC article.
Altered and allele-specific open chromatin landscape reveals epigenetic and genetic regulators of innate immunity in COVID-19.
Zhang B, Zhang Z, Koeken VACM, Kumar S, Aillaud M, Tsay HC, Liu Z, Kraft ARM, Soon CF, Odak I, Bošnjak B, Vlot A; Deutsche COVID-19 OMICS Initiative (DeCOI); Swertz MA, Ohler U, Geffers R, Illig T, Huehn J, Saliba AE, Sander LE, Förster R, Xu CJ, Cornberg M, Schulte LN, Li Y. Zhang B, et al. Among authors: ohler u. Cell Genom. 2023 Feb 8;3(2):100232. doi: 10.1016/j.xgen.2022.100232. Epub 2022 Dec 2. Cell Genom. 2023. PMID: 36474914 Free PMC article.
How to find genomic regions relevant for gene regulation.
Guo X, Ohler U, Yildirim F. Guo X, et al. Among authors: ohler u. Med Genet. 2021 Aug 14;33(2):157-165. doi: 10.1515/medgen-2021-2074. eCollection 2021 Jun. Med Genet. 2021. PMID: 38836026 Free PMC article.
Copy-number dosage regulates telomere maintenance and disease-associated pathways in neuroblastoma.
Burkert M, Blanc E, Thiessen N, Weber C, Toedling J, Monti R, Dombrowe VM, Stella de Biase M, Kaufmann TL, Haase K, Waszak SM, Eggert A, Beule D, Schulte JH, Ohler U, Schwarz RF. Burkert M, et al. Among authors: ohler u. iScience. 2024 Sep 10;27(10):110918. doi: 10.1016/j.isci.2024.110918. eCollection 2024 Oct 18. iScience. 2024. PMID: 39635126 Free PMC article.
Metadata-guided feature disentanglement for functional genomics.
Rakowski A, Monti R, Huryn V, Lemanczyk M, Ohler U, Lippert C. Rakowski A, et al. Among authors: ohler u. Bioinformatics. 2024 Sep 1;40(Suppl 2):ii4-ii10. doi: 10.1093/bioinformatics/btae403. Bioinformatics. 2024. PMID: 39230700 Free PMC article.
146 results