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Adipocyte lipin 1 is positively associated with metabolic health in humans and regulates systemic metabolism in mice.
LaPoint A, Singer JM, Ferguson D, Shew TM, Renkemeyer MK, Palacios H, Field R, Shankaran M, Smith GI, Yoshino J, He M, Patti GJ, Hellerstein MK, Klein S, Brestoff JR, Finck BN, Lutkewitte AJ. LaPoint A, et al. Among authors: finck bn. bioRxiv [Preprint]. 2023 Feb 3:2023.02.01.526676. doi: 10.1101/2023.02.01.526676. bioRxiv. 2023. Update in: J Clin Invest. 2024 Oct 15;134(23):e169722. doi: 10.1172/JCI169722 PMID: 36778276 Free PMC article. Updated. Preprint.
Silencing alanine transaminase 2 in diabetic liver attenuates hyperglycemia by reducing gluconeogenesis from amino acids.
Martino MR, Gutiérrez-Aguilar M, Yiew NKH, Lutkewitte AJ, Singer JM, McCommis KS, Ferguson D, Liss KHH, Yoshino J, Renkemeyer MK, Smith GI, Cho K, Fletcher JA, Klein S, Patti GJ, Burgess SC, Finck BN. Martino MR, et al. Among authors: finck bn. Cell Rep. 2022 Nov 15;41(7):111633. doi: 10.1016/j.celrep.2022.111633. Cell Rep. 2022. PMID: 36384117 Free PMC article. No abstract available.
Mitochondrial Pyruvate Carrier Inhibition Attenuates Hepatic Stellate Cell Activation and Liver Injury in a Mouse Model of Metabolic Dysfunction-associated Steatotic Liver Disease.
Habibi M, Ferguson D, Eichler SJ, Chan MM, LaPoint A, Shew TM, He M, Lutkewitte AJ, Schilling JD, Cho KY, Patti GJ, Finck BN. Habibi M, et al. Among authors: finck bn. bioRxiv [Preprint]. 2023 Aug 25:2023.02.13.528384. doi: 10.1101/2023.02.13.528384. bioRxiv. 2023. PMID: 36824926 Free PMC article. Preprint.
Steatosis drives monocyte-derived macrophage accumulation in human metabolic dysfunction-associated fatty liver disease.
Chan MM, Daemen S, Beals JW, Terekhova M, Yang BQ, Fu CF, He L, Park AC, Smith GI, Razani B, Byrnes K, Beatty WL, Eckhouse SR, Eagon JC, Ferguson D, Finck BN, Klein S, Artyomov MN, Schilling JD. Chan MM, et al. Among authors: finck bn. JHEP Rep. 2023 Aug 11;5(11):100877. doi: 10.1016/j.jhepr.2023.100877. eCollection 2023 Nov. JHEP Rep. 2023. PMID: 37869071 Free PMC article.
Assays to Enhance Metabolic Phenotyping in the Kidney.
Hammoud S, Kern J, Mukherjee S, Lutkewitte A, Singh P, Newberry K, Finck BN, Gewin LS. Hammoud S, et al. Among authors: finck bn. Am J Physiol Renal Physiol. 2025 Jan 17. doi: 10.1152/ajprenal.00232.2024. Online ahead of print. Am J Physiol Renal Physiol. 2025. PMID: 39819047
Advancing mitochondrial therapeutics: Synthesis and pharmacological evaluation of pyrazole-based inhibitors targeting the mitochondrial pyruvate carrier.
Maram L, Michael JM, Politte H, Srirama VS, Hadji A, Habibi M, Kelly MO, Brookheart RT, Finck BN, Hegazy L, McCommis KS, Elgendy B. Maram L, et al. Among authors: finck bn. Eur J Med Chem. 2025 Feb 5;283:117150. doi: 10.1016/j.ejmech.2024.117150. Epub 2024 Dec 11. Eur J Med Chem. 2025. PMID: 39708766 Free article.
176 results