Desar IME - Search Results

1

The safety risk of information overload and bureaucracy in oncology clinical trial conduct.

van Ravensteijn SG, Meijerink M, Nijenhuis-van Schayk R, Desar IME, Bol KF, van Herpen CML, Verheul HMW. van Ravensteijn SG, et al. Among authors: desar ime. Eur J Cancer. 2023 Apr;183:90-94. doi: 10.1016/j.ejca.2023.01.018. Epub 2023 Jan 30. Eur J Cancer. 2023. PMID: 36812844

2

Beyond RECIST: molecular and functional imaging techniques for evaluation of response to targeted therapy.

Desar IM, van Herpen CM, van Laarhoven HW, Barentsz JO, Oyen WJ, van der Graaf WT. Desar IM, et al. Cancer Treat Rev. 2009 Jun;35(4):309-21. doi: 10.1016/j.ctrv.2008.12.001. Epub 2009 Jan 10. Cancer Treat Rev. 2009. PMID: 19136215 Review.

3

The reverse side of the victory: flare up of symptoms after discontinuation of sunitinib or sorafenib in renal cell cancer patients. A report of three cases.

Desar IM, Mulder SF, Stillebroer AB, van Spronsen DJ, van der Graaf WT, Mulders PF, van Herpen CM. Desar IM, et al. Acta Oncol. 2009;48(6):927-31. doi: 10.1080/02841860902974167. Acta Oncol. 2009. PMID: 19452305 No abstract available.

4

Case studies showing clinical signs and management of cutaneous toxicity of the MEK1/2 inhibitor AZD6244 (ARRY-142886) in patients with solid tumours.

Desar IM, Bovenschen HJ, Timmer-Bonte AJ, Cantarini MV, Van Der Graaf WT, Van Rossum MM, Van Herpen CM. Desar IM, et al. Acta Oncol. 2010;49(1):110-3. doi: 10.3109/02841860903104152. Acta Oncol. 2010. PMID: 19634052 No abstract available.

5

Phase I clinical and magnetic resonance imaging study of the vascular agent NGR-hTNF in patients with advanced cancers (European Organization for Research and Treatment of Cancer Study 16041).

van Laarhoven HW, Fiedler W, Desar IM, van Asten JJ, Marréaud S, Lacombe D, Govaerts AS, Bogaerts J, Lasch P, Timmer-Bonte JN, Lambiase A, Bordignon C, Punt CJ, Heerschap A, van Herpen CM. van Laarhoven HW, et al. Clin Cancer Res. 2010 Feb 15;16(4):1315-23. doi: 10.1158/1078-0432.CCR-09-1621. Epub 2010 Feb 9. Clin Cancer Res. 2010. PMID: 20145168 Free article. Clinical Trial.

6

The first-in-human study of the hydrogen sulfate (Hyd-sulfate) capsule of the MEK1/2 inhibitor AZD6244 (ARRY-142886): a phase I open-label multicenter trial in patients with advanced cancer.

Banerji U, Camidge DR, Verheul HM, Agarwal R, Sarker D, Kaye SB, Desar IM, Timmer-Bonte JN, Eckhardt SG, Lewis KD, Brown KH, Cantarini MV, Morris C, George SM, Smith PD, van Herpen CM. Banerji U, et al. Clin Cancer Res. 2010 Mar 1;16(5):1613-23. doi: 10.1158/1078-0432.CCR-09-2483. Epub 2010 Feb 23. Clin Cancer Res. 2010. PMID: 20179232 Free article. Clinical Trial.

7

A patient with renal cell carcinoma and thoracic pain.

Desar IM, Sonderen MJ, van Herpen CM. Desar IM, et al. Neth J Med. 2010 May;68(5):229-32. Neth J Med. 2010. PMID: 20508275 Free article. No abstract available.

8

Sorafenib reduces the percentage of tumour infiltrating regulatory T cells in renal cell carcinoma patients.

Desar IM, Jacobs JH, Hulsbergen-vandeKaa CA, Oyen WJ, Mulders PF, van der Graaf WT, Adema GJ, van Herpen CM, de Vries IJ. Desar IM, et al. Int J Cancer. 2011 Jul 15;129(2):507-12. doi: 10.1002/ijc.25674. Epub 2010 Nov 12. Int J Cancer. 2011. PMID: 20839259

9

Factors affecting the unexpected failure of DCE-MRI to determine the optimal biological dose of the vascular targeting agent NGR-hTNF in solid cancer patients.

Desar IM, van Herpen CM, van Asten JJ, Fiedler W, Marreaud S, Timmer-Bonte JN, ter Voert EG, Lambiase A, Bordignon C, Heerschap A, van Laarhoven HW. Desar IM, et al. Eur J Radiol. 2011 Dec;80(3):655-61. doi: 10.1016/j.ejrad.2010.08.045. Epub 2010 Sep 21. Eur J Radiol. 2011. PMID: 20863638

10

A Phase Ib dose-escalation study to evaluate safety and tolerability of the addition of the aminopeptidase inhibitor tosedostat (CHR-2797) to paclitaxel in patients with advanced solid tumours.

van Herpen CM, Eskens FA, de Jonge M, Desar I, Hooftman L, Bone EA, Timmer-Bonte JN, Verweij J. van Herpen CM, et al. Br J Cancer. 2010 Oct 26;103(9):1362-8. doi: 10.1038/sj.bjc.6605917. Epub 2010 Sep 28. Br J Cancer. 2010. PMID: 20877350 Free PMC article. Clinical Trial.

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