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An 19F NMR fragment-based approach for the discovery and development of BRCA2-RAD51 inhibitors to pursuit synthetic lethality in combination with PARP inhibition in pancreatic cancer.
Myers SH, Poppi L, Rinaldi F, Veronesi M, Ciamarone A, Previtali V, Bagnolini G, Schipani F, Ortega Martínez JA, Girotto S, Di Stefano G, Farabegoli F, Walsh N, De Franco F, Roberti M, Cavalli A. Myers SH, et al. Among authors: farabegoli f. Eur J Med Chem. 2024 Feb 5;265:116114. doi: 10.1016/j.ejmech.2023.116114. Epub 2023 Dec 31. Eur J Med Chem. 2024. PMID: 38194775 Free article.
Preomic profile of BxPC-3 cells after treatment with BRC4.
Previtali V, Myers SH, Poppi L, Wynne K, Casamassima I, Girotto S, Di Stefano G, Farabegoli F, Roberti M, Oliviero G, Cavalli A. Previtali V, et al. Among authors: farabegoli f. J Proteomics. 2023 Sep 30;288:104983. doi: 10.1016/j.jprot.2023.104983. Epub 2023 Aug 1. J Proteomics. 2023. PMID: 37536521
The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination.
Schipani F, Manerba M, Marotta R, Poppi L, Gennari A, Rinaldi F, Armirotti A, Farabegoli F, Roberti M, Di Stefano G, Rocchia W, Girotto S, Tirelli N, Cavalli A. Schipani F, et al. Among authors: farabegoli f. Int J Mol Sci. 2022 Jul 28;23(15):8338. doi: 10.3390/ijms23158338. Int J Mol Sci. 2022. PMID: 35955488 Free PMC article.
Lactate is a potential promoter of tamoxifen resistance in MCF7 cells.
Rossi V, Govoni M, Farabegoli F, Di Stefano G. Rossi V, et al. Among authors: farabegoli f. Biochim Biophys Acta Gen Subj. 2022 Sep;1866(9):130185. doi: 10.1016/j.bbagen.2022.130185. Epub 2022 Jun 3. Biochim Biophys Acta Gen Subj. 2022. PMID: 35661802
58 results